R01AG037637/AG/NIA NIH HHS/United States[Grants and Funding] - Search Results

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Administration of a selective β2 adrenergic receptor antagonist exacerbates neuropathology and cognitive deficits in a mouse model of Alzheimer's disease.

Branca C, Wisely EV, Hartman LK, Caccamo A, Oddo S. Branca C, et al. Neurobiol Aging. 2014 Dec;35(12):2726-2735. doi: 10.1016/j.neurobiolaging.2014.06.011. Epub 2014 Jun 16. Neurobiol Aging. 2014. PMID: 25034342 Free PMC article.

Inducing autophagy by rapamycin before, but not after, the formation of plaques and tangles ameliorates cognitive deficits.

Majumder S, Richardson A, Strong R, Oddo S. Majumder S, et al. PLoS One. 2011;6(9):e25416. doi: 10.1371/journal.pone.0025416. Epub 2011 Sep 28. PLoS One. 2011. PMID: 21980451 Free PMC article.

Lifelong rapamycin administration ameliorates age-dependent cognitive deficits by reducing IL-1β and enhancing NMDA signaling.

Majumder S, Caccamo A, Medina DX, Benavides AD, Javors MA, Kraig E, Strong R, Richardson A, Oddo S. Majumder S, et al. Aging Cell. 2012 Apr;11(2):326-35. doi: 10.1111/j.1474-9726.2011.00791.x. Epub 2012 Feb 1. Aging Cell. 2012. PMID: 22212527 Free PMC article.

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