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PI-103, a dual inhibitor of Class IA phosphatidylinositide 3-kinase and mTOR, has antileukemic activity in AML.
Leukemia. 2008 Sep;22(9):1698-706. doi: 10.1038/leu.2008.144. Epub 2008 Jun 12.
Leukemia. 2008.
PMID: 18548104
Chemical genetic blockade of transformation reveals dependence on aberrant oncogenic signaling.
Fan QW, Zhang C, Shokat KM, Weiss WA.
Fan QW, et al.
Curr Biol. 2002 Aug 20;12(16):1386-94. doi: 10.1016/s0960-9822(02)01070-9.
Curr Biol. 2002.
PMID: 12194819
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