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HCC and angiogenesis: possible targets and future directions.
Zhu AX, Duda DG, Sahani DV, Jain RK. Zhu AX, et al. Nat Rev Clin Oncol. 2011 May;8(5):292-301. doi: 10.1038/nrclinonc.2011.30. Epub 2011 Mar 8. Nat Rev Clin Oncol. 2011. PMID: 21386818 Free PMC article. Review.
AZD2171, a pan-VEGF receptor tyrosine kinase inhibitor, normalizes tumor vasculature and alleviates edema in glioblastoma patients.
Batchelor TT, Sorensen AG, di Tomaso E, Zhang WT, Duda DG, Cohen KS, Kozak KR, Cahill DP, Chen PJ, Zhu M, Ancukiewicz M, Mrugala MM, Plotkin S, Drappatz J, Louis DN, Ivy P, Scadden DT, Benner T, Loeffler JS, Wen PY, Jain RK. Batchelor TT, et al. Cancer Cell. 2007 Jan;11(1):83-95. doi: 10.1016/j.ccr.2006.11.021. Cancer Cell. 2007. PMID: 17222792 Free PMC article. Clinical Trial.
Malignant cells facilitate lung metastasis by bringing their own soil.
Duda DG, Duyverman AM, Kohno M, Snuderl M, Steller EJ, Fukumura D, Jain RK. Duda DG, et al. Proc Natl Acad Sci U S A. 2010 Dec 14;107(50):21677-82. doi: 10.1073/pnas.1016234107. Epub 2010 Nov 22. Proc Natl Acad Sci U S A. 2010. PMID: 21098274 Free PMC article.
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