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HSV-1 remodels host telomeres to facilitate viral replication.
Deng Z, Kim ET, Vladimirova O, Dheekollu J, Wang Z, Newhart A, Liu D, Myers JL, Hensley SE, Moffat J, Janicki SM, Fraser NW, Knipe DM, Weitzman MD, Lieberman PM. Deng Z, et al. Cell Rep. 2014 Dec 24;9(6):2263-78. doi: 10.1016/j.celrep.2014.11.019. Epub 2014 Dec 11. Cell Rep. 2014. PMID: 25497088 Free PMC article.
Subtelomeric p53 binding prevents accumulation of DNA damage at human telomeres.
Tutton S, Azzam GA, Stong N, Vladimirova O, Wiedmer A, Monteith JA, Beishline K, Wang Z, Deng Z, Riethman H, McMahon SB, Murphy M, Lieberman PM. Tutton S, et al. EMBO J. 2016 Jan 18;35(2):193-207. doi: 10.15252/embj.201490880. Epub 2015 Dec 12. EMBO J. 2016. PMID: 26658110 Free PMC article.
Inherited mutations in the helicase RTEL1 cause telomere dysfunction and Hoyeraal-Hreidarsson syndrome.
Deng Z, Glousker G, Molczan A, Fox AJ, Lamm N, Dheekollu J, Weizman OE, Schertzer M, Wang Z, Vladimirova O, Schug J, Aker M, Londoño-Vallejo A, Kaestner KH, Lieberman PM, Tzfati Y. Deng Z, et al. Proc Natl Acad Sci U S A. 2013 Sep 3;110(36):E3408-16. doi: 10.1073/pnas.1300600110. Epub 2013 Aug 19. Proc Natl Acad Sci U S A. 2013. PMID: 23959892 Free PMC article.
CTCF binding site sequence differences are associated with unique regulatory and functional trends during embryonic stem cell differentiation.
Plasschaert RN, Vigneau S, Tempera I, Gupta R, Maksimoska J, Everett L, Davuluri R, Mamorstein R, Lieberman PM, Schultz D, Hannenhalli S, Bartolomei MS. Plasschaert RN, et al. Nucleic Acids Res. 2014 Jan;42(2):774-89. doi: 10.1093/nar/gkt910. Epub 2013 Oct 10. Nucleic Acids Res. 2014. PMID: 24121688 Free PMC article.