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Capsid-modified adenoviral vectors for improved muscle-directed gene therapy.
Guse K, Suzuki M, Sule G, Bertin TK, Tyynismaa H, Ahola-Erkkilä S, Palmer D, Suomalainen A, Ng P, Cerullo V, Hemminki A, Lee B. Guse K, et al. Hum Gene Ther. 2012 Oct;23(10):1065-70. doi: 10.1089/hum.2012.003. Epub 2012 Aug 13. Hum Gene Ther. 2012. PMID: 22888960 Free PMC article.
One-year expression from high-capacity adenoviral vectors in the brains of animals with pre-existing anti-adenoviral immunity: clinical implications.
Barcia C, Jimenez-Dalmaroni M, Kroeger KM, Puntel M, Rapaport AJ, Larocque D, King GD, Johnson SA, Liu C, Xiong W, Candolfi M, Mondkar S, Ng P, Palmer D, Castro MG, Lowenstein PR. Barcia C, et al. Mol Ther. 2007 Dec;15(12):2154-63. doi: 10.1038/sj.mt.6300305. Epub 2007 Sep 25. Mol Ther. 2007. PMID: 17895861 Free PMC article.
Herpes simplex virus type 1 thymidine kinase sequence fused to the lacz gene increases levels of {beta}-galactosidase activity per genome of high-capacity but not first-generation adenoviral vectors in vitro and in vivo.
Puntel M, Barrett RJ, Mondkar S, Saxena V, Kroeger KM, Muhammad AK, Liu C, Bondale N, Sciascia S, Xiong W, Shi Y, Salem A, Zadmehr A, Huynh P, Palmer D, Ng P, Castro MG, Lowenstein PR. Puntel M, et al. J Virol. 2009 Feb;83(4):2004-10. doi: 10.1128/JVI.01298-08. Epub 2008 Dec 10. J Virol. 2009. PMID: 19073729 Free PMC article.