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Small molecule chemical probes of microRNA function.
Velagapudi SP, Vummidi BR, Disney MD. Velagapudi SP, et al. Curr Opin Chem Biol. 2015 Feb;24:97-103. doi: 10.1016/j.cbpa.2014.10.024. Epub 2014 Dec 10. Curr Opin Chem Biol. 2015. PMID: 25500006 Free PMC article. Review.
Discovery of a biomarker and lead small molecules to target r(GGGGCC)-associated defects in c9FTD/ALS.
Su Z, Zhang Y, Gendron TF, Bauer PO, Chew J, Yang WY, Fostvedt E, Jansen-West K, Belzil VV, Desaro P, Johnston A, Overstreet K, Oh SY, Todd PK, Berry JD, Cudkowicz ME, Boeve BF, Dickson D, Floeter MK, Traynor BJ, Morelli C, Ratti A, Silani V, Rademakers R, Brown RH, Rothstein JD, Boylan KB, Petrucelli L, Disney MD. Su Z, et al. Neuron. 2014 Sep 3;83(5):1043-50. doi: 10.1016/j.neuron.2014.07.041. Epub 2014 Aug 14. Neuron. 2014. PMID: 25132468 Free PMC article.