R01HL079027/HL/NHLBI NIH HHS/United States[Grants and Funding] - Search Results

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Amino acid residues Arg(659), Arg(660), and Tyr(661) in the spacer domain of ADAMTS13 are critical for cleavage of von Willebrand factor.

Jin SY, Skipwith CG, Zheng XL. Jin SY, et al. Blood. 2010 Mar 18;115(11):2300-10. doi: 10.1182/blood-2009-07-235101. Epub 2010 Jan 14. Blood. 2010. PMID: 20075158 Free PMC article.

Factor VIII and platelets synergistically accelerate cleavage of von Willebrand factor by ADAMTS13 under fluid shear stress.

Skipwith CG, Cao W, Zheng XL. Skipwith CG, et al. J Biol Chem. 2010 Sep 10;285(37):28596-603. doi: 10.1074/jbc.M110.131227. Epub 2010 Jul 6. J Biol Chem. 2010. PMID: 20605782 Free PMC article.

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