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Mannose-binding lectin and its associated proteases (MASPs) mediate coagulation and its deficiency is a risk factor in developing complications from infection, including disseminated intravascular coagulation.
Takahashi K, Chang WC, Takahashi M, Pavlov V, Ishida Y, La Bonte L, Shi L, Fujita T, Stahl GL, Van Cott EM. Takahashi K, et al. Immunobiology. 2011 Jan-Feb;216(1-2):96-102. doi: 10.1016/j.imbio.2010.02.005. Epub 2010 Mar 4. Immunobiology. 2011. PMID: 20399528 Free PMC article.
Complement 3 is involved with ventilator-induced lung injury.
Takahashi K, Saha D, Shattino I, Pavlov VI, Stahl GL, Finnegan P, Melo MF. Takahashi K, et al. Int Immunopharmacol. 2011 Dec;11(12):2138-43. doi: 10.1016/j.intimp.2011.09.008. Epub 2011 Oct 5. Int Immunopharmacol. 2011. PMID: 21979496 Free PMC article.