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Nanomolar-Potency Small Molecule Inhibitor of STAT5 Protein.
Cumaraswamy AA, Lewis AM, Geletu M, Todic A, Diaz DB, Cheng XR, Brown CE, Laister RC, Muench D, Kerman K, Grimes HL, Minden MD, Gunning PT. Cumaraswamy AA, et al. ACS Med Chem Lett. 2014 Sep 19;5(11):1202-1206. doi: 10.1021/ml500165r. eCollection 2014 Nov 13. ACS Med Chem Lett. 2014. PMID: 25419444 Free PMC article.
DNMT3A Haploinsufficiency Transforms FLT3ITD Myeloproliferative Disease into a Rapid, Spontaneous, and Fully Penetrant Acute Myeloid Leukemia.
Meyer SE, Qin T, Muench DE, Masuda K, Venkatasubramanian M, Orr E, Suarez L, Gore SD, Delwel R, Paietta E, Tallman MS, Fernandez H, Melnick A, Le Beau MM, Kogan S, Salomonis N, Figueroa ME, Grimes HL. Meyer SE, et al. Cancer Discov. 2016 May;6(5):501-15. doi: 10.1158/2159-8290.CD-16-0008. Epub 2016 Mar 25. Cancer Discov. 2016. PMID: 27016502 Free PMC article.