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Page 1
Genetic risk converges on regulatory networks mediating early type 2 diabetes.
Walker JT, Saunders DC, Rai V, Chen HH, Orchard P, Dai C, Pettway YD, Hopkirk AL, Reihsmann CV, Tao Y, Fan S, Shrestha S, Varshney A, Petty LE, Wright JJ, Ventresca C, Agarwala S, Aramandla R, Poffenberger G, Jenkins R, Mei S, Hart NJ, Phillips S, Kang H, Greiner DL, Shultz LD, Bottino R, Liu J, Below JE; HPAP Consortium; Parker SCJ, Powers AC, Brissova M. Walker JT, et al. Nature. 2023 Dec;624(7992):621-629. doi: 10.1038/s41586-023-06693-2. Epub 2023 Dec 4. Nature. 2023. PMID: 38049589 Free PMC article.
The Human Islet: Mini-Organ With Mega-Impact.
Walker JT, Saunders DC, Brissova M, Powers AC. Walker JT, et al. Endocr Rev. 2021 Sep 28;42(5):605-657. doi: 10.1210/endrev/bnab010. Endocr Rev. 2021. PMID: 33844836 Free PMC article. Review.
Disrupted RNA editing in beta cells mimics early-stage type 1 diabetes.
Knebel UE, Peleg S, Dai C, Cohen-Fultheim R, Jonsson S, Poznyak K, Israeli M, Zamashanski L, Glaser B, Levanon EY, Powers AC, Klochendler A, Dor Y. Knebel UE, et al. Cell Metab. 2024 Jan 2;36(1):48-61.e6. doi: 10.1016/j.cmet.2023.11.011. Epub 2023 Dec 20. Cell Metab. 2024. PMID: 38128529 Free article.
Pancreatic islet α cell function and proliferation requires the arginine transporter SLC7A2.
Spears E, Stanley JE, Shou M, Yin L, Li X, Dai C, Bradley A, Sellick K, Poffenberger G, Coate KC, Shrestha S, Jenkins R, Sloop KW, Wilson KT, Attie AD, Keller MP, Chen W, Powers AC, Dean ED. Spears E, et al. bioRxiv [Preprint]. 2023 Aug 14:2023.08.10.552656. doi: 10.1101/2023.08.10.552656. bioRxiv. 2023. PMID: 37645716 Free PMC article. Preprint.
Replicative capacity of β-cells and type 1 diabetes.
Saunders D, Powers AC. Saunders D, et al. J Autoimmun. 2016 Jul;71:59-68. doi: 10.1016/j.jaut.2016.03.014. Epub 2016 Apr 28. J Autoimmun. 2016. PMID: 27133598 Free PMC article. Review.
Human islet T cells are highly reactive to preproinsulin in type 1 diabetes.
Anderson AM, Landry LG, Alkanani AA, Pyle L, Powers AC, Atkinson MA, Mathews CE, Roep BO, Michels AW, Nakayama M. Anderson AM, et al. Proc Natl Acad Sci U S A. 2021 Oct 12;118(41):e2107208118. doi: 10.1073/pnas.2107208118. Proc Natl Acad Sci U S A. 2021. PMID: 34611019 Free PMC article.
60 results