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Decreasing the intrinsically disordered protein α-synuclein levels by targeting its structured mRNA with a ribonuclease-targeting chimera.
Tong Y, Zhang P, Yang X, Liu X, Zhang J, Grudniewska M, Jung I, Abegg D, Liu J, Childs-Disney JL, Gibaut QMR, Haniff HS, Adibekian A, Mouradian MM, Disney MD. Tong Y, et al. Proc Natl Acad Sci U S A. 2024 Jan 9;121(2):e2306682120. doi: 10.1073/pnas.2306682120. Epub 2024 Jan 5. Proc Natl Acad Sci U S A. 2024. PMID: 38181056 Free PMC article.
Nucleic Acid-Based Therapeutics for Parkinson's Disease.
Nakamori M, Junn E, Mochizuki H, Mouradian MM. Nakamori M, et al. Neurotherapeutics. 2019 Apr;16(2):287-298. doi: 10.1007/s13311-019-00714-7. Neurotherapeutics. 2019. PMID: 30756362 Free PMC article. Review.
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