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Page 1
Flexizyme-Enabled Benchtop Biosynthesis of Thiopeptides.
Fleming SR, Bartges TE, Vinogradov AA, Kirkpatrick CL, Goto Y, Suga H, Hicks LM, Bowers AA. Fleming SR, et al. J Am Chem Soc. 2019 Jan 16;141(2):758-762. doi: 10.1021/jacs.8b11521. Epub 2019 Jan 8. J Am Chem Soc. 2019. PMID: 30602112 Free PMC article.
Enzymatic Pyridine Aromatization during Thiopeptide Biosynthesis.
Rice AJ, Pelton JM, Kramer NJ, Catlin DS, Nair SK, Pogorelov TV, Mitchell DA, Bowers AA. Rice AJ, et al. J Am Chem Soc. 2022 Nov 23;144(46):21116-21124. doi: 10.1021/jacs.2c07377. Epub 2022 Nov 9. J Am Chem Soc. 2022. PMID: 36351243 Free PMC article.
Discovery and Development of Cyclic Peptide Inhibitors of CIB1.
Haberman VA, Fleming SR, Leisner TM, Puhl AC, Feng E, Xie L, Chen X, Goto Y, Suga H, Parise LV, Kireev D, Pearce KH, Bowers AA. Haberman VA, et al. ACS Med Chem Lett. 2021 Oct 27;12(11):1832-1839. doi: 10.1021/acsmedchemlett.1c00438. eCollection 2021 Nov 11. ACS Med Chem Lett. 2021. PMID: 34795874 Free PMC article.
Identification of Covalent Cyclic Peptide Inhibitors in mRNA Display.
Iskandar SE, Chiou LF, Leisner TM, Shell DJ, Norris-Drouin JL, Vaziri C, Pearce KH, Bowers AA. Iskandar SE, et al. J Am Chem Soc. 2023 Jul 19;145(28):15065-15070. doi: 10.1021/jacs.3c04833. Epub 2023 Jul 3. J Am Chem Soc. 2023. PMID: 37395736 Free PMC article.
Cheminformatics-Guided Cell-Free Exploration of Peptide Natural Products.
Pelton JM, Hochuli JE, Sadecki PW, Katoh T, Suga H, Hicks LM, Muratov EN, Tropsha A, Bowers AA. Pelton JM, et al. J Am Chem Soc. 2024 Mar 27;146(12):8016-8030. doi: 10.1021/jacs.3c11306. Epub 2024 Mar 12. J Am Chem Soc. 2024. PMID: 38470819 Free PMC article.
19 results