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The APE2 nuclease is essential for DNA double-strand break repair by microhomology-mediated end joining.
Fleury H, MacEachern MK, Stiefel CM, Anand R, Sempeck C, Nebenfuehr B, Maurer-Alcalá K, Ball K, Proctor B 3rd, Belan O, Taylor E, Ortega R, Dodd B, Weatherly L, Dansoko D, Leung JW, Boulton SJ, Arnoult N. Fleury H, et al. Mol Cell. 2023 May 4;83(9):1429-1445.e8. doi: 10.1016/j.molcel.2023.03.017. Epub 2023 Apr 11. Mol Cell. 2023. PMID: 37044098 Free PMC article.
Evolved histone tail regulates 53BP1 recruitment at damaged chromatin.
Kelliher JL, Folkerts ML, Shen KV, Song W, Tengler K, Stiefel CM, Lee SO, Dray E, Zhao W, Koss B, Pannunzio NR, Leung JW. Kelliher JL, et al. Nat Commun. 2024 May 31;15(1):4634. doi: 10.1038/s41467-024-49071-w. Nat Commun. 2024. PMID: 38821984 Free PMC article.
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