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Dicer inactivation in osteoprogenitor cells compromises fetal survival and bone formation, while excision in differentiated osteoblasts increases bone mass in the adult mouse.
Gaur T, Hussain S, Mudhasani R, Parulkar I, Colby JL, Frederick D, Kream BE, van Wijnen AJ, Stein JL, Stein GS, Jones SN, Lian JB. Gaur T, et al. Dev Biol. 2010 Apr 1;340(1):10-21. doi: 10.1016/j.ydbio.2010.01.008. Epub 2010 Jan 15. Dev Biol. 2010. PMID: 20079730 Free PMC article.