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Page 1
Histone serotonylation is a permissive modification that enhances TFIID binding to H3K4me3.
Farrelly LA, Thompson RE, Zhao S, Lepack AE, Lyu Y, Bhanu NV, Zhang B, Loh YE, Ramakrishnan A, Vadodaria KC, Heard KJ, Erikson G, Nakadai T, Bastle RM, Lukasak BJ, Zebroski H 3rd, Alenina N, Bader M, Berton O, Roeder RG, Molina H, Gage FH, Shen L, Garcia BA, Li H, Muir TW, Maze I. Farrelly LA, et al. Nature. 2019 Mar;567(7749):535-539. doi: 10.1038/s41586-019-1024-7. Epub 2019 Mar 13. Nature. 2019. PMID: 30867594 Free PMC article.
Chemoenzymatic Semisynthesis of Proteins.
Thompson RE, Muir TW. Thompson RE, et al. Chem Rev. 2020 Mar 25;120(6):3051-3126. doi: 10.1021/acs.chemrev.9b00450. Epub 2019 Nov 27. Chem Rev. 2020. PMID: 31774265 Free PMC article. Review.
Recurrent SMARCB1 Mutations Reveal a Nucleosome Acidic Patch Interaction Site That Potentiates mSWI/SNF Complex Chromatin Remodeling.
Valencia AM, Collings CK, Dao HT, St Pierre R, Cheng YC, Huang J, Sun ZY, Seo HS, Mashtalir N, Comstock DE, Bolonduro O, Vangos NE, Yeoh ZC, Dornon MK, Hermawan C, Barrett L, Dhe-Paganon S, Woolf CJ, Muir TW, Kadoch C. Valencia AM, et al. Cell. 2019 Nov 27;179(6):1342-1356.e23. doi: 10.1016/j.cell.2019.10.044. Epub 2019 Nov 20. Cell. 2019. PMID: 31759698 Free PMC article.
Chromatin as a key consumer in the metabolite economy.
Diehl KL, Muir TW. Diehl KL, et al. Nat Chem Biol. 2020 Jun;16(6):620-629. doi: 10.1038/s41589-020-0517-x. Epub 2020 May 22. Nat Chem Biol. 2020. PMID: 32444835 Free PMC article. Review.
Chemical biology approaches to study histone interactors.
Burton AJ, Hamza GM, Zhang AX, Muir TW. Burton AJ, et al. Biochem Soc Trans. 2021 Nov 1;49(5):2431-2441. doi: 10.1042/BST20210772. Biochem Soc Trans. 2021. PMID: 34709376 Free PMC article. Review.
TGM2-mediated histone transglutamination is dictated by steric accessibility.
Lukasak BJ, Mitchener MM, Kong L, Dul BE, Lazarus CD, Ramakrishnan A, Ni J, Shen L, Maze I, Muir TW. Lukasak BJ, et al. Proc Natl Acad Sci U S A. 2022 Oct 25;119(43):e2208672119. doi: 10.1073/pnas.2208672119. Epub 2022 Oct 18. Proc Natl Acad Sci U S A. 2022. PMID: 36256821 Free PMC article.
Protein engineering through tandem transamidation.
Thompson RE, Stevens AJ, Muir TW. Thompson RE, et al. Nat Chem. 2019 Aug;11(8):737-743. doi: 10.1038/s41557-019-0281-2. Epub 2019 Jul 1. Nat Chem. 2019. PMID: 31263208 Free PMC article.
69 results