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Cholesterol accumulation in tissues of the Niemann-pick type C mouse is determined by the rate of lipoprotein-cholesterol uptake through the coated-pit pathway in each organ.
Proc Natl Acad Sci U S A. 1999 Oct 12;96(21):11992-7. doi: 10.1073/pnas.96.21.11992.
Proc Natl Acad Sci U S A. 1999.
PMID: 10518564
Free PMC article.
Selective neurodegeneration, without neurofibrillary tangles, in a mouse model of Niemann-Pick C disease.
German DC, Quintero EM, Liang CL, Ng B, Punia S, Xie C, Dietschy JM.
German DC, et al.
J Comp Neurol. 2001 May 7;433(3):415-25. doi: 10.1002/cne.1149.
J Comp Neurol. 2001.
PMID: 11298365
Free PMC article.
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