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Respiratory mucosal immunity against SARS-CoV-2 after mRNA vaccination.
Tang J, Zeng C, Cox TM, Li C, Son YM, Cheon IS, Wu Y, Behl S, Taylor JJ, Chakaraborty R, Johnson AJ, Shiavo DN, Utz JP, Reisenauer JS, Midthun DE, Mullon JJ, Edell ES, Alameh MG, Borish L, Teague WG, Kaplan MH, Weissman D, Kern R, Hu H, Vassallo R, Liu SL, Sun J. Tang J, et al. Sci Immunol. 2022 Oct 28;7(76):eadd4853. doi: 10.1126/sciimmunol.add4853. Epub 2022 Oct 21. Sci Immunol. 2022. PMID: 35857583 Free PMC article.
TREM2 mediates MHCII-associated CD4+ T-cell response against gliomas.
Zheng J, Wang L, Zhao S, Zhang W, Chang Y, Bosco DB, Huang T, Dheer A, Gao S, Xu S, Ayasoufi K, Al-Kharboosh R, Qi F, Xie M, Johnson AJ, Dong H, Quiñones-Hinojosa A, Wu LJ. Zheng J, et al. Neuro Oncol. 2024 May 3;26(5):811-825. doi: 10.1093/neuonc/noad214. Neuro Oncol. 2024. PMID: 37941134 Free PMC article.
Immune signatures underlying post-acute COVID-19 lung sequelae.
Cheon IS, Li C, Son YM, Goplen NP, Wu Y, Cassmann T, Wang Z, Wei X, Tang J, Li Y, Marlow H, Hughes S, Hammel L, Cox TM, Goddery E, Ayasoufi K, Weiskopf D, Boonyaratanakornkit J, Dong H, Li H, Chakraborty R, Johnson AJ, Edell E, Taylor JJ, Kaplan MH, Sette A, Bartholmai BJ, Kern R, Vassallo R, Sun J. Cheon IS, et al. Sci Immunol. 2021 Nov 12;6(65):eabk1741. doi: 10.1126/sciimmunol.abk1741. Epub 2021 Nov 12. Sci Immunol. 2021. PMID: 34591653 Free PMC article. Clinical Trial.
Rejuvenation of the aged brain immune cell landscape in mice through p16-positive senescent cell clearance.
Zhang X, Pearsall VM, Carver CM, Atkinson EJ, Clarkson BDS, Grund EM, Baez-Faria M, Pavelko KD, Kachergus JM, White TA, Johnson RK, Malo CS, Gonzalez-Suarez AM, Ayasoufi K, Johnson KO, Tritz ZP, Fain CE, Khadka RH, Ogrodnik M, Jurk D, Zhu Y, Tchkonia T, Revzin A, Kirkland JL, Johnson AJ, Howe CL, Thompson EA, LeBrasseur NK, Schafer MJ. Zhang X, et al. Nat Commun. 2022 Sep 27;13(1):5671. doi: 10.1038/s41467-022-33226-8. Nat Commun. 2022. PMID: 36167854 Free PMC article.
Brain resident memory T cells rapidly expand and initiate neuroinflammatory responses following CNS viral infection.
Ayasoufi K, Wolf DM, Namen SL, Jin F, Tritz ZP, Pfaller CK, Zheng J, Goddery EN, Fain CE, Gulbicki LR, Borchers AL, Reesman RA, Yokanovich LT, Maynes MA, Bamkole MA, Khadka RH, Hansen MJ, Wu LJ, Johnson AJ. Ayasoufi K, et al. Brain Behav Immun. 2023 Aug;112:51-76. doi: 10.1016/j.bbi.2023.05.009. Epub 2023 May 24. Brain Behav Immun. 2023. PMID: 37236326 Free PMC article.
Microglial P2Y6 calcium signaling promotes phagocytosis and shapes neuroimmune responses in epileptogenesis.
Umpierre AD, Li B, Ayasoufi K, Zhao S, Xie M, Thyen G, Hur B, Zheng J, Liang Y, Wu Z, Yu X, Sung J, Johnson AJ, Li Y, Wu LJ. Umpierre AD, et al. bioRxiv [Preprint]. 2023 Jun 13:2023.06.12.544691. doi: 10.1101/2023.06.12.544691. bioRxiv. 2023. Update in: Neuron. 2024 Jun 19;112(12):1959-1977.e10. doi: 10.1016/j.neuron.2024.03.017. PMID: 37398001 Free PMC article. Updated. Preprint.
Discrete class I molecules on brain endothelium differentially regulate neuropathology in experimental cerebral malaria.
Fain CE, Zheng J, Jin F, Ayasoufi K, Wu Y, Lilley MT, Dropik AR, Wolf DM, Rodriguez RC, Aibaidula A, Tritz ZP, Bouchal SM, Pewe LL, Urban SL, Chen Y, Chang SY, Hansen MJ, Kachergus JM, Shi J, Thompson EA, Jensen HE, Harty JT, Parney IF, Sun J, Wu LJ, Johnson AJ. Fain CE, et al. Brain. 2024 Feb 1;147(2):566-589. doi: 10.1093/brain/awad319. Brain. 2024. PMID: 37776513
12 results