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SR-B1 drives endothelial cell LDL transcytosis via DOCK4 to promote atherosclerosis.
Huang L, Chambliss KL, Gao X, Yuhanna IS, Behling-Kelly E, Bergaya S, Ahmed M, Michaely P, Luby-Phelps K, Darehshouri A, Xu L, Fisher EA, Ge WP, Mineo C, Shaul PW. Huang L, et al. Nature. 2019 May;569(7757):565-569. doi: 10.1038/s41586-019-1140-4. Epub 2019 Apr 24. Nature. 2019. PMID: 31019307 Free PMC article.
Transiently structured head domains control intermediate filament assembly.
Zhou X, Lin Y, Kato M, Mori E, Liszczak G, Sutherland L, Sysoev VO, Murray DT, Tycko R, McKnight SL. Zhou X, et al. Proc Natl Acad Sci U S A. 2021 Feb 23;118(8):e2022121118. doi: 10.1073/pnas.2022121118. Proc Natl Acad Sci U S A. 2021. PMID: 33593918 Free PMC article.
Hepatic malonyl-CoA synthesis restrains gluconeogenesis by suppressing fat oxidation, pyruvate carboxylation, and amino acid availability.
Deja S, Fletcher JA, Kim CW, Kucejova B, Fu X, Mizerska M, Villegas M, Pudelko-Malik N, Browder N, Inigo-Vollmer M, Menezes CJ, Mishra P, Berglund ED, Browning JD, Thyfault JP, Young JD, Horton JD, Burgess SC. Deja S, et al. Cell Metab. 2024 May 7;36(5):1088-1104.e12. doi: 10.1016/j.cmet.2024.02.004. Epub 2024 Mar 5. Cell Metab. 2024. PMID: 38447582 Free article.
Adipocyte iron levels impinge on a fat-gut crosstalk to regulate intestinal lipid absorption and mediate protection from obesity.
Zhang Z, Funcke JB, Zi Z, Zhao S, Straub LG, Zhu Y, Zhu Q, Crewe C, An YA, Chen S, Li N, Wang MY, Ghaben AL, Lee C, Gautron L, Engelking LJ, Raj P, Deng Y, Gordillo R, Kusminski CM, Scherer PE. Zhang Z, et al. Cell Metab. 2021 Aug 3;33(8):1624-1639.e9. doi: 10.1016/j.cmet.2021.06.001. Epub 2021 Jun 25. Cell Metab. 2021. PMID: 34174197 Free PMC article.
82 results