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Inhibiting DNA methylation and RNA editing upregulates immunogenic RNA to transform the tumor microenvironment and prolong survival in ovarian cancer.
Gomez S, Cox OL, Walker RR 3rd, Rentia U, Hadley M, Arthofer E, Diab N, Grundy EE, Kanholm T, McDonald JI, Kobyra J, Palmer E, Noonepalle S, Villagra A, Leitenberg D, Bollard CM, Saunthararajah Y, Chiappinelli KB. Gomez S, et al. J Immunother Cancer. 2022 Nov;10(11):e004974. doi: 10.1136/jitc-2022-004974. J Immunother Cancer. 2022. PMID: 36343976 Free PMC article.
Prostate cancer cell-platelet bidirectional signaling promotes calcium mobilization, invasion and apoptotic resistance via distinct receptor-ligand pairs.
Garofano K, Rashid K, Smith M, Brantner C, Suwunnakorn S, Diemert D, Gordon O, Horvath A, Khan S, Popratiloff A, Rhim J, Sidahmed A, Maggirwar SB, O'Brien TJ, Perera MA, Lee NH. Garofano K, et al. Sci Rep. 2023 Feb 17;13(1):2864. doi: 10.1038/s41598-023-29450-x. Sci Rep. 2023. PMID: 36806315 Free PMC article.
The HIV latency reversing agent HODHBt inhibits the phosphatases PTPN1 and PTPN2.
Howard JN, Zaikos TD, Levinger C, Rivera E, McMahon EK, Holmberg CS, Terao J, Sanz M, Copertino DC Jr, Wang W, Soriano-Sarabia N, Jones RB, Bosque A. Howard JN, et al. JCI Insight. 2024 Aug 8;9(18):e179680. doi: 10.1172/jci.insight.179680. JCI Insight. 2024. PMID: 39115957 Free PMC article.
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