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Mitochondrial Dysfunction, Depleted Purinergic Signaling, and Defective T Cell Vigilance and Immune Defense.
J Infect Dis. 2016 Feb 1;213(3):456-64. doi: 10.1093/infdis/jiv373. Epub 2015 Jul 6.
J Infect Dis. 2016.
PMID: 26150546
Free PMC article.
Mitochondria are gate-keepers of T cell function by producing the ATP that drives purinergic signaling.
Ledderose C, Bao Y, Lidicky M, Zipperle J, Li L, Strasser K, Shapiro NI, Junger WG.
Ledderose C, et al.
J Biol Chem. 2014 Sep 12;289(37):25936-45. doi: 10.1074/jbc.M114.575308. Epub 2014 Jul 28.
J Biol Chem. 2014.
PMID: 25070895
Free PMC article.
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