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Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4.
Immunity. 1995 Nov;3(5):541-7. doi: 10.1016/1074-7613(95)90125-6.
Immunity. 1995.
PMID: 7584144
Free article.
Defects in B lymphocyte maturation and T lymphocyte activation in mice lacking Jak3.
Thomis DC, Gurniak CB, Tivol E, Sharpe AH, Berg LJ.
Thomis DC, et al.
Science. 1995 Nov 3;270(5237):794-7. doi: 10.1126/science.270.5237.794.
Science. 1995.
PMID: 7481767
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