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Romidepsin and Afatinib Abrogate Jak-Signal Transducer and Activator of Transcription Signaling and Elicit Synergistic Antitumor Effects in Cutaneous T-Cell Lymphoma.
Shih BB, Ma C, Cortes JR, Reglero C, Miller H, Quinn SA, Albero R, Laurent AP, Mackey A, Ferrando AA, Geskin L, Palomero T. Shih BB, et al. J Invest Dermatol. 2024 Jul;144(7):1579-1589.e8. doi: 10.1016/j.jid.2023.12.010. Epub 2024 Jan 14. J Invest Dermatol. 2024. PMID: 38219917 Free article.
Oncogenic Vav1-Myo1f induces therapeutically targetable macrophage-rich tumor microenvironment in peripheral T cell lymphoma.
Cortes JR, Filip I, Albero R, Patiño-Galindo JA, Quinn SA, Lin WW, Laurent AP, Shih BB, Brown JA, Cooke AJ, Mackey A, Einson J, Zairis S, Rivas-Delgado A, Laginestra MA, Pileri S, Campo E, Bhagat G, Ferrando AA, Rabadan R, Palomero T. Cortes JR, et al. Cell Rep. 2022 Apr 19;39(3):110695. doi: 10.1016/j.celrep.2022.110695. Cell Rep. 2022. PMID: 35443168 Free PMC article.
Genetic mechanisms of HLA-I loss and immune escape in diffuse large B cell lymphoma.
Fangazio M, Ladewig E, Gomez K, Garcia-Ibanez L, Kumar R, Teruya-Feldstein J, Rossi D, Filip I, Pan-Hammarström Q, Inghirami G, Boldorini R, Ott G, Staiger AM, Chapuy B, Gaidano G, Bhagat G, Basso K, Rabadan R, Pasqualucci L, Dalla-Favera R. Fangazio M, et al. Proc Natl Acad Sci U S A. 2021 Jun 1;118(22):e2104504118. doi: 10.1073/pnas.2104504118. Proc Natl Acad Sci U S A. 2021. PMID: 34050029 Free PMC article.
Pervasiveness of HLA allele-specific expression loss across tumor types.
Filip I, Wang A, Kravets O, Orenbuch R, Zhao J, Perea-Chamblee TE, Manji GA, López de Maturana E, Malats N, Olive KP, Rabadan R. Filip I, et al. Genome Med. 2023 Feb 9;15(1):8. doi: 10.1186/s13073-023-01154-x. Genome Med. 2023. PMID: 36759885 Free PMC article.
GET: a foundation model of transcription across human cell types.
Fu X, Mo S, Buendia A, Laurent A, Shao A, Del Mar Alvarez-Torres M, Yu T, Tan J, Su J, Sagatelian R, Ferrando AA, Ciccia A, Lan Y, Owens DM, Palomero T, Xing EP, Rabadan R. Fu X, et al. bioRxiv [Preprint]. 2024 Jul 3:2023.09.24.559168. doi: 10.1101/2023.09.24.559168. bioRxiv. 2024. PMID: 39005360 Free PMC article. Preprint.