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Pan-cancer T cell atlas links a cellular stress response state to immunotherapy resistance.
Chu Y, Dai E, Li Y, Han G, Pei G, Ingram DR, Thakkar K, Qin JJ, Dang M, Le X, Hu C, Deng Q, Sinjab A, Gupta P, Wang R, Hao D, Peng F, Yan X, Liu Y, Song S, Zhang S, Heymach JV, Reuben A, Elamin YY, Pizzi MP, Lu Y, Lazcano R, Hu J, Li M, Curran M, Futreal A, Maitra A, Jazaeri AA, Ajani JA, Swanton C, Cheng XD, Abbas HA, Gillison M, Bhat K, Lazar AJ, Green M, Litchfield K, Kadara H, Yee C, Wang L. Chu Y, et al. Nat Med. 2023 Jun;29(6):1550-1562. doi: 10.1038/s41591-023-02371-y. Epub 2023 May 29. Nat Med. 2023. PMID: 37248301 Free PMC article.
An atlas of epithelial cell states and plasticity in lung adenocarcinoma.
Han G, Sinjab A, Rahal Z, Lynch AM, Treekitkarnmongkol W, Liu Y, Serrano AG, Feng J, Liang K, Khan K, Lu W, Hernandez SD, Liu Y, Cao X, Dai E, Pei G, Hu J, Abaya C, Gomez-Bolanos LI, Peng F, Chen M, Parra ER, Cascone T, Sepesi B, Moghaddam SJ, Scheet P, Negrao MV, Heymach JV, Li M, Dubinett SM, Stevenson CS, Spira AE, Fujimoto J, Solis LM, Wistuba II, Chen J, Wang L, Kadara H. Han G, et al. Nature. 2024 Mar;627(8004):656-663. doi: 10.1038/s41586-024-07113-9. Epub 2024 Feb 28. Nature. 2024. PMID: 38418883 Free PMC article.
The Single-Cell Immunogenomic Landscape of B and Plasma Cells in Early-Stage Lung Adenocarcinoma.
Hao D, Han G, Sinjab A, Gomez-Bolanos LI, Lazcano R, Serrano A, Hernandez SD, Dai E, Cao X, Hu J, Dang M, Wang R, Chu Y, Song X, Zhang J, Parra ER, Wargo JA, Swisher SG, Cascone T, Sepesi B, Futreal AP, Li M, Dubinett SM, Fujimoto J, Solis Soto LM, Wistuba II, Stevenson CS, Spira A, Shalapour S, Kadara H, Wang L. Hao D, et al. Cancer Discov. 2022 Nov 2;12(11):2626-2645. doi: 10.1158/2159-8290.CD-21-1658. Cancer Discov. 2022. PMID: 36098652 Free PMC article.
Cell-by-Cell: Unlocking Lung Cancer Pathogenesis.
Sinjab A, Rahal Z, Kadara H. Sinjab A, et al. Cancers (Basel). 2022 Jul 14;14(14):3424. doi: 10.3390/cancers14143424. Cancers (Basel). 2022. PMID: 35884485 Free PMC article. Review.
METI: deep profiling of tumor ecosystems by integrating cell morphology and spatial transcriptomics.
Jiang J, Liu Y, Qin J, Chen J, Wu J, Pizzi MP, Lazcano R, Yamashita K, Xu Z, Pei G, Cho KS, Chu Y, Sinjab A, Peng F, Yan X, Han G, Wang R, Dai E, Dai Y, Czerniak BA, Futreal A, Maitra A, Lazar A, Kadara H, Jazaeri AA, Cheng X, Ajani J, Gao J, Hu J, Wang L. Jiang J, et al. Nat Commun. 2024 Aug 25;15(1):7312. doi: 10.1038/s41467-024-51708-9. Nat Commun. 2024. PMID: 39181865 Free PMC article.
Game of clones: Battles in the field of carcinogenesis.
Rahal Z, Sinjab A, Wistuba II, Kadara H. Rahal Z, et al. Pharmacol Ther. 2022 Sep;237:108251. doi: 10.1016/j.pharmthera.2022.108251. Epub 2022 Jul 15. Pharmacol Ther. 2022. PMID: 35850404 Free PMC article. Review.