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A PSGL-1 glycomimetic reduces thrombus burden without affecting hemostasis.
Wong DJ, Park DD, Park SS, Haller CA, Chen J, Dai E, Liu L, Mandhapati AR, Eradi P, Dhakal B, Wever WJ, Hanes M, Sun L, Cummings RD, Chaikof EL. Wong DJ, et al. Blood. 2021 Sep 30;138(13):1182-1193. doi: 10.1182/blood.2020009428. Blood. 2021. PMID: 33945603 Free PMC article.
Convergent Synthesis of Sialyl LewisX- O-Core-1 Threonine.
Sardar MYR, Mandhapati AR, Park S, Wever WJ, Cummings RD, Chaikof EL. Sardar MYR, et al. J Org Chem. 2018 May 4;83(9):4963-4972. doi: 10.1021/acs.joc.7b03117. Epub 2018 Apr 23. J Org Chem. 2018. PMID: 29638128 Free PMC article.
Glycopeptide analogues of PSGL-1 inhibit P-selectin in vitro and in vivo.
Krishnamurthy VR, Sardar MY, Ying Y, Song X, Haller C, Dai E, Wang X, Hanjaya-Putra D, Sun L, Morikis V, Simon SI, Woods RJ, Cummings RD, Chaikof EL. Krishnamurthy VR, et al. Nat Commun. 2015 Mar 31;6:6387. doi: 10.1038/ncomms7387. Nat Commun. 2015. PMID: 25824568 Free PMC article.