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Single-cell analysis reveals transcriptomic remodellings in distinct cell types that contribute to human prostate cancer progression.
Chen S, Zhu G, Yang Y, Wang F, Xiao YT, Zhang N, Bian X, Zhu Y, Yu Y, Liu F, Dong K, Mariscal J, Liu Y, Soares F, Loo Yau H, Zhang B, Chen W, Wang C, Chen D, Guo Q, Yi Z, Liu M, Fraser M, De Carvalho DD, Boutros PC, Di Vizio D, Jiang Z, van der Kwast T, Berlin A, Wu S, Wang J, He HH, Ren S. Chen S, et al. Nat Cell Biol. 2021 Jan;23(1):87-98. doi: 10.1038/s41556-020-00613-6. Epub 2021 Jan 8. Nat Cell Biol. 2021. PMID: 33420488
A clinically applicable integrative molecular classification of meningiomas.
Nassiri F, Liu J, Patil V, Mamatjan Y, Wang JZ, Hugh-White R, Macklin AM, Khan S, Singh O, Karimi S, Corona RI, Liu LY, Chen CY, Chakravarthy A, Wei Q, Mehani B, Suppiah S, Gao A, Workewych AM, Tabatabai G, Boutros PC, Bader GD, de Carvalho DD, Kislinger T, Aldape K, Zadeh G. Nassiri F, et al. Nature. 2021 Sep;597(7874):119-125. doi: 10.1038/s41586-021-03850-3. Epub 2021 Aug 25. Nature. 2021. PMID: 34433969
The genomic and evolutionary landscapes of anaplastic thyroid carcinoma.
Zeng PYF, Prokopec SD, Lai SY, Pinto N, Chan-Seng-Yue MA, Clifton-Bligh R, Williams MD, Howlett CJ, Plantinga P, Cecchini MJ, Lam AK, Siddiqui I, Wang J, Sun RX, Watson JD, Korah R, Carling T, Agrawal N, Cipriani N, Ball D, Nelkin B, Rooper LM, Bishop JA, Garnis C, Berean K, Nicolson NG, Weinberger P, Henderson YC, Lalansingh CM, Tian M, Yamaguchi TN, Livingstone J, Salcedo A, Patel K, Vizeacoumar F, Datti A, Xi L, Nikiforov YE, Smallridge R, Copland JA, Marlow LA, Hyrcza MD, Delbridge L, Sidhu S, Sywak M, Robinson B, Fung K, Ghasemi F, Kwan K, MacNeil SD, Mendez A, Palma DA, Khan MI, Shaikh M, Ruicci KM, Wehrli B, Winquist E, Yoo J, Mymryk JS, Rocco JW, Wheeler D, Scherer S, Giordano TJ, Barrett JW, Faquin WC, Gill AJ, Clayman G, Boutros PC, Nichols AC. Zeng PYF, et al. Cell Rep. 2024 Mar 26;43(3):113826. doi: 10.1016/j.celrep.2024.113826. Epub 2024 Feb 26. Cell Rep. 2024. PMID: 38412093 Free PMC article.
Drug screening at single-organoid resolution via bioprinting and interferometry.
Tebon PJ, Wang B, Markowitz AL, Davarifar A, Tsai BL, Krawczuk P, Gonzalez AE, Sartini S, Murray GF, Nguyen HTL, Tavanaie N, Nguyen TL, Boutros PC, Teitell MA, Soragni A. Tebon PJ, et al. Nat Commun. 2023 Jun 6;14(1):3168. doi: 10.1038/s41467-023-38832-8. Nat Commun. 2023. PMID: 37280220 Free PMC article.
Prostate cancer reshapes the secreted and extracellular vesicle urinary proteomes.
Khoo A, Govindarajan M, Qiu Z, Liu LY, Ignatchenko V, Waas M, Macklin A, Keszei A, Neu S, Main BP, Yang L, Lance RS, Downes MR, Semmes OJ, Vesprini D, Liu SK, Nyalwidhe JO, Boutros PC, Kislinger T. Khoo A, et al. Nat Commun. 2024 Jun 13;15(1):5069. doi: 10.1038/s41467-024-49424-5. Nat Commun. 2024. PMID: 38871730 Free PMC article.
The telomere length landscape of prostate cancer.
Livingstone J, Shiah YJ, Yamaguchi TN, Heisler LE, Huang V, Lesurf R, Gebo T, Carlin B, Eng S, Drysdale E, Green J, van der Kwast T, Bristow RG, Fraser M, Boutros PC. Livingstone J, et al. Nat Commun. 2021 Nov 25;12(1):6893. doi: 10.1038/s41467-021-27223-6. Nat Commun. 2021. PMID: 34824250 Free PMC article.
Federated benchmarking of medical artificial intelligence with MedPerf.
Karargyris A, Umeton R, Sheller MJ, Aristizabal A, George J, Wuest A, Pati S, Kassem H, Zenk M, Baid U, Narayana Moorthy P, Chowdhury A, Guo J, Nalawade S, Rosenthal J, Kanter D, Xenochristou M, Beutel DJ, Chung V, Bergquist T, Eddy J, Abid A, Tunstall L, Sanseviero O, Dimitriadis D, Qian Y, Xu X, Liu Y, Goh RSM, Bala S, Bittorf V, Reddy Puchala S, Ricciuti B, Samineni S, Sengupta E, Chaudhari A, Coleman C, Desinghu B, Diamos G, Dutta D, Feddema D, Fursin G, Huang X, Kashyap S, Lane N, Mallick I; FeTS Consortium; BraTS-2020 Consortium; AI4SafeChole Consortium; Mascagni P, Mehta V, Ferro Moraes C, Natarajan V, Nikolov N, Padoy N, Pekhimenko G, Reddi VJ, Reina GA, Ribalta P, Singh A, Thiagarajan JJ, Albrecht J, Wolf T, Miller G, Fu H, Shah P, Xu D, Yadav P, Talby D, Awad MM, Howard JP, Rosenthal M, Marchionni L, Loda M, Johnson JM, Bakas S, Mattson P. Karargyris A, et al. Nat Mach Intell. 2023 Jul;5(7):799-810. doi: 10.1038/s42256-023-00652-2. Epub 2023 Jul 17. Nat Mach Intell. 2023. PMID: 38706981 Free PMC article.
A polygenic two-hit hypothesis for prostate cancer.
Houlahan KE, Livingstone J, Fox NS, Kurganovs N, Zhu H, Sietsma Penington J, Jung CH, Yamaguchi TN, Heisler LE, Jovelin R, Costello AJ, Pope BJ, Kishan AU, Corcoran NM, Bristow RG, Waszak SM, Weischenfeldt J, He HH, Hung RJ, Hovens CM, Boutros PC. Houlahan KE, et al. J Natl Cancer Inst. 2023 Apr 11;115(4):468-472. doi: 10.1093/jnci/djad001. J Natl Cancer Inst. 2023. PMID: 36610996 Free PMC article.
The proteomic landscape of glioblastoma recurrence reveals novel and targetable immunoregulatory drivers.
Tatari N, Khan S, Livingstone J, Zhai K, Mckenna D, Ignatchenko V, Chokshi C, Gwynne WD, Singh M, Revill S, Mikolajewicz N, Zhu C, Chan J, Hawkins C, Lu JQ, Provias JP, Ask K, Morrissy S, Brown S, Weiss T, Weller M, Han H, Greenspoon JN, Moffat J, Venugopal C, Boutros PC, Singh SK, Kislinger T. Tatari N, et al. Acta Neuropathol. 2022 Dec;144(6):1127-1142. doi: 10.1007/s00401-022-02506-4. Epub 2022 Sep 30. Acta Neuropathol. 2022. PMID: 36178522 Free PMC article.
The Proteogenomics of Prostate Cancer Radioresistance.
Haas R, Frame G, Khan S, Neilsen BK, Hong BH, Yeo CPX, Yamaguchi TN, Ong EHW, Zhao W, Carlin B, Yeo ELL, Tan KM, Bugh YZ, Zhu C, Hugh-White R, Livingstone J, Poon DJJ, Chu PL, Patel Y, Tao S, Ignatchenko V, Kurganovs NJ, Higgins GS, Downes MR, Loblaw A, Vesprini D, Kishan AU, Chua MLK, Kislinger T, Boutros PC, Liu SK. Haas R, et al. Cancer Res Commun. 2024 Sep 1;4(9):2463-2479. doi: 10.1158/2767-9764.CRC-24-0292. Cancer Res Commun. 2024. PMID: 39166898 Free PMC article.
34 results