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Page 1
Structural variations in cancer and the 3D genome.
Dubois F, Sidiropoulos N, Weischenfeldt J, Beroukhim R. Dubois F, et al. Nat Rev Cancer. 2022 Sep;22(9):533-546. doi: 10.1038/s41568-022-00488-9. Epub 2022 Jun 28. Nat Rev Cancer. 2022. PMID: 35764888 Free PMC article. Review.
Cancer aneuploidies are shaped primarily by effects on tumour fitness.
Shih J, Sarmashghi S, Zhakula-Kostadinova N, Zhang S, Georgis Y, Hoyt SH, Cuoco MS, Gao GF, Spurr LF, Berger AC, Ha G, Rendo V, Shen H, Meyerson M, Cherniack AD, Taylor AM, Beroukhim R. Shih J, et al. Nature. 2023 Jul;619(7971):793-800. doi: 10.1038/s41586-023-06266-3. Epub 2023 Jun 28. Nature. 2023. PMID: 37380777 Free PMC article.
A genetic basis for cancer sex differences revealed in Xp11 translocation renal cell carcinoma.
Achom M, Sadagopan A, Bao C, McBride F, Xu Q, Konda P, Tourdot RW, Li J, Nakhoul M, Gallant DS, Ahmed UA, O'Toole J, Freeman D, Mary Lee GS, Hecht JL, Kauffman EC, Einstein DJ, Choueiri TK, Zhang CZ, Viswanathan SR. Achom M, et al. bioRxiv [Preprint]. 2023 Aug 6:2023.08.04.552029. doi: 10.1101/2023.08.04.552029. bioRxiv. 2023. Update in: Cell. 2024 Oct 3;187(20):5735-5752.e25. doi: 10.1016/j.cell.2024.07.038. PMID: 37577497 Free PMC article. Updated. Preprint.
Tangent normalization for somatic copy-number inference in cancer genome analysis.
Gao GF, Oh C, Saksena G, Deng D, Westlake LC, Hill BA, Reich M, Schumacher SE, Berger AC, Carter SL, Cherniack AD, Meyerson M, Tabak B, Beroukhim R, Getz G. Gao GF, et al. Bioinformatics. 2022 Oct 14;38(20):4677-4686. doi: 10.1093/bioinformatics/btac586. Bioinformatics. 2022. PMID: 36040167 Free PMC article.
Whole-genome characterization of lung adenocarcinomas lacking alterations in the RTK/RAS/RAF pathway.
Carrot-Zhang J, Yao X, Devarakonda S, Deshpande A, Damrauer JS, Silva TC, Wong CK, Choi HY, Felau I, Robertson AG, Castro MAA, Bao L, Rheinbay E, Liu EM, Trieu T, Haan D, Yau C, Hinoue T, Liu Y, Shapira O, Kumar K, Mungall KL, Zhang H, June-Koo Lee J, Berger A, Gao GF, Zhitomirsky B, Liang WW, Zhou M, Moorthi S, Berger AH, Collisson EA, Zody MC, Ding L, Cherniack AD, Getz G, Elemento O, Benz CC, Stuart J, Zenklusen JC, Beroukhim R, Chang JC, Campbell JD, Hayes DN, Yang L, Laird PW, Weinstein JN, Kwiatkowski DJ, Tsao MS, Travis WD, Khurana E, Berman BP, Hoadley KA, Robine N; TCGA Research Network; Meyerson M, Govindan R, Imielinski M. Carrot-Zhang J, et al. Cell Rep. 2021 Feb 23;34(8):108784. doi: 10.1016/j.celrep.2021.108784. Cell Rep. 2021. PMID: 33626341 Free PMC article. No abstract available.
High-Resolution Profiling of Lung Adenocarcinoma Identifies Expression Subtypes with Specific Biomarkers and Clinically Relevant Vulnerabilities.
Roh W, Geffen Y, Cha H, Miller M, Anand S, Kim J, Heiman DI, Gainor JF, Laird PW, Cherniack AD, Ock CY, Lee SH, Getz G; National Cancer Institute Center for Cancer Genomics Tumor Molecular Pathology (TMP) Analysis Working Group. Roh W, et al. Cancer Res. 2022 Nov 2;82(21):3917-3931. doi: 10.1158/0008-5472.CAN-22-0432. Cancer Res. 2022. PMID: 36040373 Free PMC article.