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Page 1
Polymer nanoparticles deliver mRNA to the lung for mucosal vaccination.
Suberi A, Grun MK, Mao T, Israelow B, Reschke M, Grundler J, Akhtar L, Lee T, Shin K, Piotrowski-Daspit AS, Homer RJ, Iwasaki A, Suh HW, Saltzman WM. Suberi A, et al. Sci Transl Med. 2023 Aug 16;15(709):eabq0603. doi: 10.1126/scitranslmed.abq0603. Epub 2023 Aug 16. Sci Transl Med. 2023. PMID: 37585505 Free PMC article.
The NIH Somatic Cell Genome Editing program.
Saha K, Sontheimer EJ, Brooks PJ, Dwinell MR, Gersbach CA, Liu DR, Murray SA, Tsai SQ, Wilson RC, Anderson DG, Asokan A, Banfield JF, Bankiewicz KS, Bao G, Bulte JWM, Bursac N, Campbell JM, Carlson DF, Chaikof EL, Chen ZY, Cheng RH, Clark KJ, Curiel DT, Dahlman JE, Deverman BE, Dickinson ME, Doudna JA, Ekker SC, Emborg ME, Feng G, Freedman BS, Gamm DM, Gao G, Ghiran IC, Glazer PM, Gong S, Heaney JD, Hennebold JD, Hinson JT, Khvorova A, Kiani S, Lagor WR, Lam KS, Leong KW, Levine JE, Lewis JA, Lutz CM, Ly DH, Maragh S, McCray PB Jr, McDevitt TC, Mirochnitchenko O, Morizane R, Murthy N, Prather RS, Ronald JA, Roy S, Roy S, Sabbisetti V, Saltzman WM, Santangelo PJ, Segal DJ, Shimoyama M, Skala MC, Tarantal AF, Tilton JC, Truskey GA, Vandsburger M, Watts JK, Wells KD, Wolfe SA, Xu Q, Xue W, Yi G, Zhou J; SCGE Consortium. Saha K, et al. Nature. 2021 Apr;592(7853):195-204. doi: 10.1038/s41586-021-03191-1. Epub 2021 Apr 7. Nature. 2021. PMID: 33828315 Free PMC article. Review.
Polymeric vehicles for nucleic acid delivery.
Piotrowski-Daspit AS, Kauffman AC, Bracaglia LG, Saltzman WM. Piotrowski-Daspit AS, et al. Adv Drug Deliv Rev. 2020;156:119-132. doi: 10.1016/j.addr.2020.06.014. Epub 2020 Jun 23. Adv Drug Deliv Rev. 2020. PMID: 32585159 Free PMC article. Review.
Nucleic Acid Delivery to the Vascular Endothelium.
Reschke M, Piotrowski-Daspit AS, Pober JS, Saltzman WM. Reschke M, et al. Mol Pharm. 2022 Dec 5;19(12):4466-4486. doi: 10.1021/acs.molpharmaceut.2c00653. Epub 2022 Oct 17. Mol Pharm. 2022. PMID: 36251765 Free PMC article. Review.
Nanoparticles for delivery of agents to fetal lungs.
Ullrich SJ, Freedman-Weiss M, Ahle S, Mandl HK, Piotrowski-Daspit AS, Roberts K, Yung N, Maassel N, Bauer-Pisani T, Ricciardi AS, Egan ME, Glazer PM, Saltzman WM, Stitelman DH. Ullrich SJ, et al. Acta Biomater. 2021 Mar 15;123:346-353. doi: 10.1016/j.actbio.2021.01.024. Epub 2021 Jan 21. Acta Biomater. 2021. PMID: 33484911 Free PMC article.
PEGylation of poly(amine-co-ester) polyplexes for tunable gene delivery.
Grun MK, Suberi A, Shin K, Lee T, Gomerdinger V, Moscato ZM, Piotrowski-Daspit AS, Saltzman WM. Grun MK, et al. Biomaterials. 2021 May;272:120780. doi: 10.1016/j.biomaterials.2021.120780. Epub 2021 Mar 24. Biomaterials. 2021. PMID: 33813260 Free PMC article.
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