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5-Fluorouracil Enhances the Antitumor Activity of the Glutaminase Inhibitor CB-839 against PIK3CA-Mutant Colorectal Cancers.
Zhao Y, Feng X, Chen Y, Selfridge JE, Gorityala S, Du Z, Wang JM, Hao Y, Cioffi G, Conlon RA, Barnholtz-Sloan JS, Saltzman J, Krishnamurthi SS, Vinayak S, Veigl M, Xu Y, Bajor DL, Markowitz SD, Meropol NJ, Eads JR, Wang Z. Zhao Y, et al. Cancer Res. 2020 Nov 1;80(21):4815-4827. doi: 10.1158/0008-5472.CAN-20-0600. Epub 2020 Sep 9. Cancer Res. 2020. PMID: 32907836 Free PMC article. Clinical Trial.
ELF3 is an antagonist of oncogenic-signalling-induced expression of EMT-TF ZEB1.
Liu D, Skomorovska Y, Song J, Bowler E, Harris R, Ravasz M, Bai S, Ayati M, Tamai K, Koyuturk M, Yuan X, Wang Z, Wang Y, Ewing RM. Liu D, et al. Cancer Biol Ther. 2019;20(1):90-100. doi: 10.1080/15384047.2018.1507256. Epub 2018 Aug 27. Cancer Biol Ther. 2019. PMID: 30148686 Free PMC article.