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Multitarget 1,4-Dioxane Compounds Combining Favorable D2-like and 5-HT1A Receptor Interactions with Potential for the Treatment of Parkinson's Disease or Schizophrenia.
Del Bello F, Ambrosini D, Bonifazi A, Newman AH, Keck TM, Giannella M, Giorgioni G, Piergentili A, Cappellacci L, Cilia A, Franchini S, Quaglia W. Del Bello F, et al. ACS Chem Neurosci. 2019 May 15;10(5):2222-2228. doi: 10.1021/acschemneuro.8b00677. Epub 2019 Jan 9. ACS Chem Neurosci. 2019. PMID: 30609891 Free PMC article.
Structure of the dopamine D3 receptor bound to a bitopic agonist reveals a new specificity site in an expanded allosteric pocket.
Arroyo-Urea S, Nazarova AL, Carrión-Antolí Á, Bonifazi A, Battiti FO, Lam JH, Newman AH, Katritch V, García-Nafría J. Arroyo-Urea S, et al. Res Sq [Preprint]. 2023 Dec 19:rs.3.rs-3433207. doi: 10.21203/rs.3.rs-3433207/v1. Res Sq. 2023. Update in: Nat Commun. 2024 Sep 5;15(1):7759. doi: 10.1038/s41467-024-51993-4 PMID: 38196573 Free PMC article. Updated. Preprint.
33 results