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2007 3
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25 results

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Page 1
Analysis of protein-coding genetic variation in 60,706 humans.
Lek M, Karczewski KJ, Minikel EV, Samocha KE, Banks E, Fennell T, O'Donnell-Luria AH, Ware JS, Hill AJ, Cummings BB, Tukiainen T, Birnbaum DP, Kosmicki JA, Duncan LE, Estrada K, Zhao F, Zou J, Pierce-Hoffman E, Berghout J, Cooper DN, Deflaux N, DePristo M, Do R, Flannick J, Fromer M, Gauthier L, Goldstein J, Gupta N, Howrigan D, Kiezun A, Kurki MI, Moonshine AL, Natarajan P, Orozco L, Peloso GM, Poplin R, Rivas MA, Ruano-Rubio V, Rose SA, Ruderfer DM, Shakir K, Stenson PD, Stevens C, Thomas BP, Tiao G, Tusie-Luna MT, Weisburd B, Won HH, Yu D, Altshuler DM, Ardissino D, Boehnke M, Danesh J, Donnelly S, Elosua R, Florez JC, Gabriel SB, Getz G, Glatt SJ, Hultman CM, Kathiresan S, Laakso M, McCarroll S, McCarthy MI, McGovern D, McPherson R, Neale BM, Palotie A, Purcell SM, Saleheen D, Scharf JM, Sklar P, Sullivan PF, Tuomilehto J, Tsuang MT, Watkins HC, Wilson JG, Daly MJ, MacArthur DG; Exome Aggregation Consortium. Lek M, et al. Nature. 2016 Aug 18;536(7616):285-91. doi: 10.1038/nature19057. Nature. 2016. PMID: 27535533 Free PMC article.
Type 2 Diabetes Variants Disrupt Function of SLC16A11 through Two Distinct Mechanisms.
Rusu V, Hoch E, Mercader JM, Tenen DE, Gymrek M, Hartigan CR, DeRan M, von Grotthuss M, Fontanillas P, Spooner A, Guzman G, Deik AA, Pierce KA, Dennis C, Clish CB, Carr SA, Wagner BK, Schenone M, Ng MCY, Chen BH; MEDIA Consortium; SIGMA T2D Consortium; Centeno-Cruz F, Zerrweck C, Orozco L, Altshuler DM, Schreiber SL, Florez JC, Jacobs SBR, Lander ES. Rusu V, et al. Cell. 2017 Jun 29;170(1):199-212.e20. doi: 10.1016/j.cell.2017.06.011. Cell. 2017. PMID: 28666119 Free PMC article.
Hypoalphalipoproteinemia in populations of Native American ancestry: an opportunity to assess the interaction of genes and the environment.
Aguilar-Salinas CA, Canizales-Quinteros S, Rojas-Martínez R, Mehta R, Villarreal-Molina MT, Arellano-Campos O, Riba L, Gómez-Pérez FJ, Tusié-Luna MT. Aguilar-Salinas CA, et al. Among authors: arellano campos o. Curr Opin Lipidol. 2009 Apr;20(2):92-7. doi: 10.1097/mol.0b013e3283295e96. Curr Opin Lipidol. 2009. PMID: 19280764 Review.
Genome-wide association study of colorectal cancer in Hispanics.
Schmit SL, Schumacher FR, Edlund CK, Conti DV, Ihenacho U, Wan P, Van Den Berg D, Casey G, Fortini BK, Lenz HJ, Tusié-Luna T, Aguilar-Salinas CA, Moreno-Macías H, Huerta-Chagoya A, Ordóñez-Sánchez ML, Rodríguez-Guillén R, Cruz-Bautista I, Rodríguez-Torres M, Muñóz-Hernández LL, Arellano-Campos O, Gómez D, Alvirde U, González-Villalpando C, González-Villalpando ME, Le Marchand L, Haiman CA, Figueiredo JC. Schmit SL, et al. Among authors: arellano campos o. Carcinogenesis. 2016 Jun;37(6):547-556. doi: 10.1093/carcin/bgw046. Epub 2016 Apr 18. Carcinogenesis. 2016. PMID: 27207650 Free PMC article.
Increased visceral fat accumulation modifies the effect of insulin resistance on arterial stiffness and hypertension risk.
Antonio-Villa NE, Bello-Chavolla OY, Vargas-Vázquez A, Mehta R, Fermín-Martínez CA, Martagón-Rosado AJ, Barquera-Guevara DA, Aguilar-Salinas CA; Metabolic Syndrome Study Group. Antonio-Villa NE, et al. Nutr Metab Cardiovasc Dis. 2021 Feb 8;31(2):506-517. doi: 10.1016/j.numecd.2020.09.031. Epub 2020 Oct 15. Nutr Metab Cardiovasc Dis. 2021. PMID: 33279372
Amerindian-specific regions under positive selection harbour new lipid variants in Latinos.
Ko A, Cantor RM, Weissglas-Volkov D, Nikkola E, Reddy PM, Sinsheimer JS, Pasaniuc B, Brown R, Alvarez M, Rodriguez A, Rodriguez-Guillen R, Bautista IC, Arellano-Campos O, Muñoz-Hernández LL, Salomaa V, Kaprio J, Jula A, Jauhiainen M, Heliövaara M, Raitakari O, Lehtimäki T, Eriksson JG, Perola M, Lohmueller KE, Matikainen N, Taskinen MR, Rodriguez-Torres M, Riba L, Tusie-Luna T, Aguilar-Salinas CA, Pajukanta P. Ko A, et al. Among authors: arellano campos o. Nat Commun. 2014 Jun 2;5:3983. doi: 10.1038/ncomms4983. Nat Commun. 2014. PMID: 24886709 Free PMC article.
Clinical characterization of data-driven diabetes subgroups in Mexicans using a reproducible machine learning approach.
Bello-Chavolla OY, Bahena-López JP, Vargas-Vázquez A, Antonio-Villa NE, Márquez-Salinas A, Fermín-Martínez CA, Rojas R, Mehta R, Cruz-Bautista I, Hernández-Jiménez S, García-Ulloa AC, Almeda-Valdes P, Aguilar-Salinas CA; Metabolic Syndrome Study Group; Group of Study CAIPaDi. Bello-Chavolla OY, et al. BMJ Open Diabetes Res Care. 2020 Jul;8(1):e001550. doi: 10.1136/bmjdrc-2020-001550. BMJ Open Diabetes Res Care. 2020. PMID: 32699108 Free PMC article.
Contribution of Known Genetic Risk Variants to Dyslipidemias and Type 2 Diabetes in Mexico: A Population-Based Nationwide Study.
Huerta-Chagoya A, Moreno-Macías H, Sevilla-González M, Rodríguez-Guillén R, Ordóñez-Sánchez ML, Gómez-Velasco D, Muñóz-Hernández L, Segura-Kato Y, Arellano-Campos O, Cruz-Bautista I, Aguilar-Salinas CA, Tusié-Luna T. Huerta-Chagoya A, et al. Among authors: arellano campos o. Genes (Basel). 2020 Jan 20;11(1):114. doi: 10.3390/genes11010114. Genes (Basel). 2020. PMID: 31968565 Free PMC article. Clinical Trial.
Mexican Carriers of the HNF1A p.E508K Variant Do Not Experience an Enhanced Response to Sulfonylureas.
Martagón AJ, Bello-Chavolla OY, Arellano-Campos O, Almeda-Valdés P, Walford GA, Cruz-Bautista I, Gómez-Velasco DV, Mehta R, Muñoz-Hernández L, Sevilla-González M, Viveros-Ruiz TL, Ordoñez-Sánchez ML, Rodríguez-Guillen R, Florez JC, Tusié-Luna MT, Aguilar-Salinas CA; Slim Initiative in Genomic Medicine for the Americas (SIGMA) Type 2 Diabetes Consortium. Martagón AJ, et al. Among authors: arellano campos o. Diabetes Care. 2018 Aug;41(8):1726-1731. doi: 10.2337/dc18-0384. Epub 2018 May 29. Diabetes Care. 2018. PMID: 29844095
25 results