Determinants of adenomyosis in women who underwent hysterectomy for benign gynecological conditions: results from a prospective multicentric study in Italy

Eur J Obstet Gynecol Reprod Biol. 2009 Apr;143(2):103-6. doi: 10.1016/j.ejogrb.2008.12.010. Epub 2009 Feb 18.

Abstract

Objective: We conducted a cross-sectional study on the frequency and risk factors for adenomyosis in women who underwent hysterectomy for benign gynecological conditions.

Study design: All women who consecutively underwent hysterectomy during the study period for benign gynecological conditions at 18 gynecological departments were eligible for the study. A total of 820 women entered the study. Pathological data were collected prospectically.

Results: Adenomyosis was identified in 231 women (28.2%, 95% confidence interval, CI, 24.6-32.5). The frequency of adenomyosis was similar in women with indication for surgery fibroids/menorrhagia (143 cases, 28.5%) or genital prolapse (69 cases, 28.2%). The rate ratio (RR) of adenomyosis was 1.9 (95% CI 1.2-2.8) in women reporting one or more induced abortions, in comparison with those reporting no induced abortion. Women with adenomyosis reported more frequently dysmenorrhoea and chronic pelvic pain, but not dyspareunia.

Conclusions: This study shows that adenomyosis is common in women who undergo hysterectomy and that it is more frequent among women reporting induced abortions dysmenorrhoea and chronic pelvic pain.

Publication types

  • Multicenter Study

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Cross-Sectional Studies
  • Dysmenorrhea / complications
  • Endometriosis / epidemiology*
  • Female
  • Humans
  • Hysterectomy / adverse effects*
  • Italy
  • Leiomyoma / surgery*
  • Menorrhagia / surgery*
  • Middle Aged
  • Pelvic Pain / complications
  • Prevalence
  • Prospective Studies
  • Risk Factors
  • Uterine Prolapse / surgery*