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Page 1
Anti-Inflammatory Effects and Photo- and Neuro-Protective Properties of BIO203, a New Amide Conjugate of Norbixin, in Development for the Treatment of Age-Related Macular Degeneration (AMD).
Fontaine V, Balducci C, Dinan L, Monteiro E, Boumedine T, Fournié M, Nguyen V, Guibout L, Clatot J, Latil M, Veillet S, Sahel JA, Lafont R, Dilda PJ, Camelo S. Fontaine V, et al. Among authors: fournie m. Int J Mol Sci. 2023 Mar 10;24(6):5296. doi: 10.3390/ijms24065296. Int J Mol Sci. 2023. PMID: 36982372 Free PMC article.
RAR Inhibitors Display Photo-Protective and Anti-Inflammatory Effects in A2E Stimulated RPE Cells In Vitro through Non-Specific Modulation of PPAR or RXR Transactivation.
Fontaine V, Boumedine T, Monteiro E, Fournié M, Gersende G, Sahel JA, Picaud S, Veillet S, Lafont R, Latil M, Dilda PJ, Camelo S. Fontaine V, et al. Among authors: fournie m. Int J Mol Sci. 2024 Mar 6;25(5):3037. doi: 10.3390/ijms25053037. Int J Mol Sci. 2024. PMID: 38474284 Free PMC article.
A2E-induced inflammation and angiogenesis in RPE cells in vitro are modulated by PPAR-α, -β/δ, -γ, and RXR antagonists and by norbixin.
Fontaine V, Fournié M, Monteiro E, Boumedine T, Balducci C, Guibout L, Latil M, Sahel JA, Veillet S, Dilda PJ, Lafont R, Camelo S. Fontaine V, et al. Among authors: fournie m. Aging (Albany NY). 2021 Sep 20;13(18):22040-22058. doi: 10.18632/aging.203558. Epub 2021 Sep 20. Aging (Albany NY). 2021. PMID: 34544906 Free PMC article.
Systemic administration of the di-apocarotenoid norbixin (BIO201) is neuroprotective, preserves photoreceptor function and inhibits A2E and lipofuscin accumulation in animal models of age-related macular degeneration and Stargardt disease.
Fontaine V, Monteiro E, Fournié M, Brazhnikova E, Boumedine T, Vidal C, Balducci C, Guibout L, Latil M, Dilda PJ, Veillet S, Sahel JA, Lafont R, Camelo S. Fontaine V, et al. Among authors: fournie m. Aging (Albany NY). 2020 Apr 7;12(7):6151-6171. doi: 10.18632/aging.103014. Epub 2020 Apr 7. Aging (Albany NY). 2020. PMID: 32255762 Free PMC article.
Impact of a quality improvement program on primary healthcare in Canada: a mixed-method evaluation.
Harris SB, Green ME, Brown JB, Roberts S, Russell G, Fournie M, Webster-Bogaert S, Paquette-Warren J, Kotecha J, Han H, Thind A, Stewart M, Reichert S, Tompkins JW, Birtwhistle R. Harris SB, et al. Among authors: fournie m. Health Policy. 2015 Apr;119(4):405-16. doi: 10.1016/j.healthpol.2014.10.019. Epub 2014 Nov 5. Health Policy. 2015. PMID: 25476553 Free article.
28 results