Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1975 2
1977 2
1983 4
1984 1
1985 3
1987 3
1988 1
1991 2
1992 2
1993 1
1995 1
1996 1
1997 3
1999 1
2000 1
2001 1
2003 2
2004 1
2006 1
2008 2
2009 4
2010 3
2011 1
2012 4
2013 5
2014 3
2015 2
2016 6
2017 11
2018 6
2019 9
2020 6
2021 8
2022 5
2023 11
2024 4

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

110 results

Results by year

Filters applied: . Clear all
Page 1
Showing results for hb s pro
Search for He S Prof instead (1 results)
Sickle Cell Disease.
Bender MA, Carlberg K. Bender MA, et al. 2003 Sep 15 [updated 2023 Dec 28]. In: Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993–2024. 2003 Sep 15 [updated 2023 Dec 28]. In: Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993–2024. PMID: 20301551 Free Books & Documents. Review.
Hb S/S (homozygous p.Glu6Val in HBB) accounts for the majority of SCD. Other forms of SCD result from compound heterozygosity for HbS with other specific pathogenic beta globin chain variants (e.g., sickle-hemoglobin C disease [Hb S/C], …
Hb S/S (homozygous p.Glu6Val in HBB) accounts for the majority of SCD. Other forms of SCD result from compound heterozygosity …
The Red Blood Cell-Inflammation Vicious Circle in Sickle Cell Disease.
Nader E, Romana M, Connes P. Nader E, et al. Front Immunol. 2020 Mar 13;11:454. doi: 10.3389/fimmu.2020.00454. eCollection 2020. Front Immunol. 2020. PMID: 32231672 Free PMC article. Review.
Sickle cell disease (SCD) is a genetic disease caused by a single mutation in the beta-globin gene, leading to the production of an abnormal hemoglobin called hemoglobin S (HbS), which polymerizes under deoxygenation, and induces the sickling of red blood cel …
Sickle cell disease (SCD) is a genetic disease caused by a single mutation in the beta-globin gene, leading to the production of an a …
Le globule rouge drépanocytaire : données fonctionnelles: The sickle red blood cell: functional data.
Connes P, Nader E. Connes P, et al. Rev Med Interne. 2023 Nov;44(4S1):4S18-4S23. doi: 10.1016/S0248-8663(23)01305-X. Rev Med Interne. 2023. PMID: 38049242 French.
Sickle cell anemia is a genetic disorder that affects hemoglobin leading to the production of an abnormal hemoglobin, called HbS. ...The pro-inflammatory and pro-oxidant state, as well as the repeated polymerization of HbS, accelerate the senesc …
Sickle cell anemia is a genetic disorder that affects hemoglobin leading to the production of an abnormal hemoglobin, c …
Genetic regulation of fetal hemoglobin across global populations.
Cato LD, Li R, Lu HY, Yu F, Wissman M, Mkumbe BS, Ekwattanakit S, Deelen P, Mwita L, Sangeda R, Suksangpleng T, Riolueang S, Bronson PG, Paul DS, Kawabata E, Astle WJ, Aguet F, Ardlie K, de Lapuente Portilla AL, Kang G, Zhang Y, Nouraie SM, Gordeuk VR, Gladwin MT, Garrett ME, Ashley-Koch A, Telen MJ, Custer B, Kelly S, Dinardo CL, Sabino EC, Loureiro P, Carneiro-Proietti AB, Maximo C; NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium; BIOS Consortium; Méndez A, Hammerer-Lercher A, Sheehan VA, Weiss MJ, Franke L, Nilsson B, Butterworth AS, Viprakasit V, Nkya S, Sankaran VG. Cato LD, et al. medRxiv [Preprint]. 2023 Mar 28:2023.03.24.23287659. doi: 10.1101/2023.03.24.23287659. medRxiv. 2023. PMID: 36993312 Free PMC article. Preprint.
Human genetic variation has enabled the identification of several key regulators of fetal-to-adult hemoglobin switching, including BCL11A, resulting in therapeutic advances. However, despite the progress made, limited further insights have been obtained to provide a fuller …
Human genetic variation has enabled the identification of several key regulators of fetal-to-adult hemoglobin switching, including BC …
Facilitation of Hb S polymerization by the substitution of Glu for Gln at beta 121.
Adachi K, Kim J, Ballas S, Surrey S, Asakura T. Adachi K, et al. J Biol Chem. 1988 Apr 25;263(12):5607-10. J Biol Chem. 1988. PMID: 2895770 Free article.
It is known that patients with Hb S-D Los Angeles have a relatively severe clinical course. Mixtures of Hb S and Hb D Los Angeles polymerized after a distinct delay time, the length of which depended on the initial hemoglobin concentration and t …
It is known that patients with Hb S-D Los Angeles have a relatively severe clinical course. Mixtures of Hb S and …
What is the future of patient-reported outcomes in sickle-cell disease?
Singh SA, Bakshi N, Mahajan P, Morris CR. Singh SA, et al. Expert Rev Hematol. 2020 Nov;13(11):1165-1173. doi: 10.1080/17474086.2020.1830370. Epub 2020 Oct 15. Expert Rev Hematol. 2020. PMID: 33034214 Free PMC article. Review.
INTRODUCTION: Sickle cell disease (SCD) is a complex, chronic disease caused by abnormal polymerization of hemoglobin, which leads to severe pain episodes, fatigue, and end-organ damage. ...Significant challenges remain in adapting PRO tools to routine clinic …
INTRODUCTION: Sickle cell disease (SCD) is a complex, chronic disease caused by abnormal polymerization of hemoglobin, which l …
Engulfment of Hb-activated platelets differentiates monocytes into pro-inflammatory macrophages in PNH patients.
Singhal R, Chawla S, Batra H, Gupta S, Ojha A, Rathore DK, Seth T, Guchhait P. Singhal R, et al. Eur J Immunol. 2018 Aug;48(8):1285-1294. doi: 10.1002/eji.201747449. Epub 2018 May 17. Eur J Immunol. 2018. PMID: 29677388 Free article.
Recently, we have described that after engulfing hemoglobin (Hb)-activated platelets, classical monocytes differentiated into pro-inflammatory phenotypes, which were abundant in the circulation of paroxysmal nocturnal hemoglobinuria (PNH) and sickle cell dise …
Recently, we have described that after engulfing hemoglobin (Hb)-activated platelets, classical monocytes differentiated into pro …
Development of pro-inflammatory phenotype in monocytes after engulfing Hb-activated platelets in hemolytic disorders.
Singhal R, Chawla S, Rathore DK, Bhasym A, Annarapu GK, Sharma V, Seth T, Guchhait P. Singhal R, et al. Clin Immunol. 2017 Feb;175:133-142. doi: 10.1016/j.clim.2016.12.007. Epub 2016 Dec 28. Clin Immunol. 2017. PMID: 28039017
Studies have described that these cells develop anti-inflammatory properties upon recycling the free-hemoglobin (Hb) in hemolytic conditions. While investigating the phenotype of monocytes in two hemolytic disorders-paroxysmal nocturnal hemoglobinuria (PNH) and sickle …
Studies have described that these cells develop anti-inflammatory properties upon recycling the free-hemoglobin (Hb) in hemolytic con …
ATP-adenosine-glutathione cross-linked hemoglobin as clinically useful oxygen carrier.
Simoni J, Simoni G, Wesson DE, Feola M. Simoni J, et al. Curr Drug Discov Technol. 2012 Sep;9(3):173-87. doi: 10.2174/157016312802650797. Curr Drug Discov Technol. 2012. PMID: 21902624 Review.
To attenuate hemoglobin's (Hb) intrinsic toxicity, Texas Tech University scientists developed a novel concept of "pharmacologic cross-linking" to formulate an effective oxygen carrier, HemoTech, which consists of purified bovine Hb cross-linked intramolecularly with ATP an …
To attenuate hemoglobin's (Hb) intrinsic toxicity, Texas Tech University scientists developed a novel concept of "pharmacologic cross …
Effect of chloride ion on the oxygen affinity of hemoglobin York (alpha 2 beta 2(146)Pro) and S-York hybrid hemoglobin (alpha 2 beta S beta York). Role of the beta 82 lysyl and beta 146 histydyl residues in chloride binding to hemoglobin.
Adachi H, Asakura T, Adachi K. Adachi H, et al. J Biol Chem. 1983 Nov 25;258(22):13422-4. J Biol Chem. 1983. PMID: 6417128 Free article.
We estimated the relative role of various chloride binding sites in determining the oxygen affinity of hemoglobin using abnormal hemoglobins such as Hb York (Hb Y) (alpha 2 beta 2(146)Pro), Hb Malmo (Hb M) (alpha 2 beta 2(97)Gln), and Hb S and chemical …
We estimated the relative role of various chloride binding sites in determining the oxygen affinity of hemoglobin using abnormal hemo …
110 results