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Page 1
Smoking changes adaptive immunity with persistent effects.
Saint-André V, Charbit B, Biton A, Rouilly V, Possémé C, Bertrand A, Rotival M, Bergstedt J, Patin E, Albert ML, Quintana-Murci L, Duffy D; Milieu Intérieur Consortium. Saint-André V, et al. Nature. 2024 Feb;626(8000):827-835. doi: 10.1038/s41586-023-06968-8. Epub 2024 Feb 14. Nature. 2024. PMID: 38355791 Free PMC article.
Autoantibodies neutralizing type I IFNs are present in ~4% of uninfected individuals over 70 years old and account for ~20% of COVID-19 deaths.
Bastard P, Gervais A, Le Voyer T, Rosain J, Philippot Q, Manry J, Michailidis E, Hoffmann HH, Eto S, Garcia-Prat M, Bizien L, Parra-Martínez A, Yang R, Haljasmägi L, Migaud M, Särekannu K, Maslovskaja J, de Prost N, Tandjaoui-Lambiotte Y, Luyt CE, Amador-Borrero B, Gaudet A, Poissy J, Morel P, Richard P, Cognasse F, Troya J, Trouillet-Assant S, Belot A, Saker K, Garçon P, Rivière JG, Lagier JC, Gentile S, Rosen LB, Shaw E, Morio T, Tanaka J, Dalmau D, Tharaux PL, Sene D, Stepanian A, Megarbane B, Triantafyllia V, Fekkar A, Heath JR, Franco JL, Anaya JM, Solé-Violán J, Imberti L, Biondi A, Bonfanti P, Castagnoli R, Delmonte OM, Zhang Y, Snow AL, Holland SM, Biggs C, Moncada-Vélez M, Arias AA, Lorenzo L, Boucherit S, Coulibaly B, Anglicheau D, Planas AM, Haerynck F, Duvlis S, Nussbaum RL, Ozcelik T, Keles S, Bousfiha AA, El Bakkouri J, Ramirez-Santana C, Paul S, Pan-Hammarström Q, Hammarström L, Dupont A, Kurolap A, Metz CN, Aiuti A, Casari G, Lampasona V, Ciceri F, Barreiros LA, Dominguez-Garrido E, Vidigal M, Zatz M, van de Beek D, Sahanic S, Tancevski I, Stepanovskyy Y, Boyarchuk O, Nukui Y, Tsumura M, Vidaur L, Tangye SG, Burrel S, Duffy D, Quintana-Murci L, Klocperk A, Kann NY,… See abstract for full author list ➔ Bastard P, et al. Sci Immunol. 2021 Aug 19;6(62):eabl4340. doi: 10.1126/sciimmunol.abl4340. Sci Immunol. 2021. PMID: 34413139 Free PMC article.
Standardized high-dimensional spectral cytometry protocol and panels for whole blood immune phenotyping in clinical and translational studies.
Dott T, Culina S, Chemali R, Mansour CA, Dubois F, Jagla B, Doisne JM, Rogge L, Huetz F, Jönsson F, Commere PH, Di Santo J, Terrier B, Quintana-Murci L, Duffy D, Hasan M; Milieu Intérieur Consortium. Dott T, et al. Cytometry A. 2024 Feb;105(2):124-138. doi: 10.1002/cyto.a.24801. Epub 2023 Oct 12. Cytometry A. 2024. PMID: 37751141
The immune factors driving DNA methylation variation in human blood.
Bergstedt J, Azzou SAK, Tsuo K, Jaquaniello A, Urrutia A, Rotival M, Lin DTS, MacIsaac JL, Kobor MS, Albert ML, Duffy D, Patin E, Quintana-Murci L; Milieu Intérieur Consortium. Bergstedt J, et al. Nat Commun. 2022 Oct 6;13(1):5895. doi: 10.1038/s41467-022-33511-6. Nat Commun. 2022. PMID: 36202838 Free PMC article.
Impact of socioeconomic status on healthy immune responses in humans.
Bertrand A, Sugrue J, Lou T, Bourke NM, Quintana-Murci L, Saint-André V, O'Farrelly C, Duffy D; Milieu Intérieur Consortium. Bertrand A, et al. Immunol Cell Biol. 2024 Aug;102(7):618-629. doi: 10.1111/imcb.12789. Epub 2024 Jun 11. Immunol Cell Biol. 2024. PMID: 38862267
Integrated analysis of whole blood oxylipin and cytokine responses after bacterial, viral, and T cell stimulation reveals new immune networks.
Villain E, Chanson A, Mainka M, Kampschulte N, Le Faouder P, Bertrand-Michel J, Brandolini-Bulon M, Charbit B, Musvosvi M, Bilek N, Scriba TJ, Quintana-Murci L, Schebb NH, Duffy D, Gladine C; Milieu Interieur Consortium. Villain E, et al. iScience. 2023 Jul 18;26(8):107422. doi: 10.1016/j.isci.2023.107422. eCollection 2023 Aug 18. iScience. 2023. PMID: 37575177 Free PMC article.
Early IFNβ secretion determines variable downstream IL-12p70 responses upon TLR4 activation.
Posseme C, Llibre A, Charbit B, Bondet V, Rouilly V, Saint-André V, Boussier J, Bergstedt J, Smith N, Townsend L, Sugrue JA, Ní Cheallaigh C, Conlon N, Rotival M, Kobor MS, Mottez E, Pol S, Patin E, Albert ML, Quintana-Murci L, Duffy D; Milieu Intérieur Consortium. Posseme C, et al. Cell Rep. 2022 Jun 28;39(13):110989. doi: 10.1016/j.celrep.2022.110989. Cell Rep. 2022. PMID: 35767946 Free PMC article.