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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1948 1
1963 1
1964 2
1965 2
1968 1
1970 3
1971 2
1972 2
1974 1
1975 1
1976 3
1978 4
1979 4
1980 1
1981 1
1982 3
1983 8
1984 6
1985 9
1986 8
1987 8
1988 2
1989 7
1990 3
1991 4
1992 11
1993 3
1994 12
1995 6
1996 14
1997 10
1998 13
1999 5
2000 9
2001 15
2002 5
2003 8
2004 11
2005 14
2006 14
2007 8
2008 11
2009 17
2010 22
2011 17
2012 20
2013 20
2014 25
2015 25
2016 24
2017 24
2018 21
2019 14
2020 20
2021 27
2022 21
2023 26
2024 16

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538 results

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Page 1
Empagliflozin, Cardiovascular Outcomes, and Mortality in Type 2 Diabetes.
Zinman B, Wanner C, Lachin JM, Fitchett D, Bluhmki E, Hantel S, Mattheus M, Devins T, Johansen OE, Woerle HJ, Broedl UC, Inzucchi SE; EMPA-REG OUTCOME Investigators. Zinman B, et al. N Engl J Med. 2015 Nov 26;373(22):2117-28. doi: 10.1056/NEJMoa1504720. Epub 2015 Sep 17. N Engl J Med. 2015. PMID: 26378978 Free article. Clinical Trial.
Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade.
McGranahan N, Furness AJ, Rosenthal R, Ramskov S, Lyngaa R, Saini SK, Jamal-Hanjani M, Wilson GA, Birkbak NJ, Hiley CT, Watkins TB, Shafi S, Murugaesu N, Mitter R, Akarca AU, Linares J, Marafioti T, Henry JY, Van Allen EM, Miao D, Schilling B, Schadendorf D, Garraway LA, Makarov V, Rizvi NA, Snyder A, Hellmann MD, Merghoub T, Wolchok JD, Shukla SA, Wu CJ, Peggs KS, Chan TA, Hadrup SR, Quezada SA, Swanton C. McGranahan N, et al. Among authors: linares j. Science. 2016 Mar 25;351(6280):1463-9. doi: 10.1126/science.aaf1490. Epub 2016 Mar 3. Science. 2016. PMID: 26940869 Free PMC article.
The lactate-NAD+ axis activates cancer-associated fibroblasts by downregulating p62.
Linares JF, Cid-Diaz T, Duran A, Osrodek M, Martinez-Ordoñez A, Reina-Campos M, Kuo HH, Elemento O, Martin ML, Cordes T, Thompson TC, Metallo CM, Moscat J, Diaz-Meco MT. Linares JF, et al. Cell Rep. 2022 May 10;39(6):110792. doi: 10.1016/j.celrep.2022.110792. Cell Rep. 2022. PMID: 35545049 Free PMC article.
PKCλ/ι Loss Induces Autophagy, Oxidative Phosphorylation, and NRF2 to Promote Liver Cancer Progression.
Kudo Y, Sugimoto M, Arias E, Kasashima H, Cordes T, Linares JF, Duran A, Nakanishi Y, Nakanishi N, L'Hermitte A, Campos A, Senni N, Rooslid T, Roberts LR, Cuervo AM, Metallo CM, Karin M, Diaz-Meco MT, Moscat J. Kudo Y, et al. Among authors: linares jf. Cancer Cell. 2020 Aug 10;38(2):247-262.e11. doi: 10.1016/j.ccell.2020.05.018. Epub 2020 Jun 25. Cancer Cell. 2020. PMID: 32589943 Free PMC article.
Stromal SOX2 Upregulation Promotes Tumorigenesis through the Generation of a SFRP1/2-Expressing Cancer-Associated Fibroblast Population.
Kasashima H, Duran A, Martinez-Ordoñez A, Nakanishi Y, Kinoshita H, Linares JF, Reina-Campos M, Kudo Y, L'Hermitte A, Yashiro M, Ohira M, Bao F, Tauriello DVF, Batlle E, Diaz-Meco MT, Moscat J. Kasashima H, et al. Among authors: linares jf. Dev Cell. 2021 Jan 11;56(1):95-110.e10. doi: 10.1016/j.devcel.2020.10.014. Epub 2020 Nov 17. Dev Cell. 2021. PMID: 33207226 Free PMC article.
Targeted immunotherapy against distinct cancer-associated fibroblasts overcomes treatment resistance in refractory HER2+ breast tumors.
Rivas EI, Linares J, Zwick M, Gómez-Llonin A, Guiu M, Labernadie A, Badia-Ramentol J, Lladó A, Bardia L, Pérez-Núñez I, Martínez-Ciarpaglini C, Tarazona N, Sallent-Aragay A, Garrido M, Celià-Terrassa T, Burgués O, Gomis RR, Albanell J, Calon A. Rivas EI, et al. Among authors: linares j. Nat Commun. 2022 Sep 9;13(1):5310. doi: 10.1038/s41467-022-32782-3. Nat Commun. 2022. PMID: 36085201 Free PMC article.
Long-term platinum-based drug accumulation in cancer-associated fibroblasts promotes colorectal cancer progression and resistance to therapy.
Linares J, Sallent-Aragay A, Badia-Ramentol J, Recort-Bascuas A, Méndez A, Manero-Rupérez N, Re DL, Rivas EI, Guiu M, Zwick M, Iglesias M, Martinez-Ciarpaglini C, Tarazona N, Varese M, Hernando-Momblona X, Cañellas-Socias A, Orrillo M, Garrido M, Saoudi N, Elez E, Navarro P, Tabernero J, Gomis RR, Batlle E, Pisonero J, Cervantes A, Montagut C, Calon A. Linares J, et al. Nat Commun. 2023 Feb 10;14(1):746. doi: 10.1038/s41467-023-36334-1. Nat Commun. 2023. PMID: 36765091 Free PMC article.
Generation of heart and vascular system in rodents by blastocyst complementation.
Coppiello G, Barlabé P, Moya-Jódar M, Abizanda G, Pogontke C, Barreda C, Iglesias E, Linares J, Arellano-Viera E, Larequi E, San Martín-Úriz P, Carvajal-Vergara X, Pelacho B, Mazo MM, Pérez-Pomares JM, Ruiz-Villalba A, Ullate-Agote A, Prósper F, Aranguren XL. Coppiello G, et al. Among authors: linares j. Dev Cell. 2023 Dec 18;58(24):2881-2895.e7. doi: 10.1016/j.devcel.2023.10.008. Epub 2023 Nov 14. Dev Cell. 2023. PMID: 37967560 Free article.
Coronary artery aneurysms, insights from the international coronary artery aneurysm registry (CAAR).
Núñez-Gil IJ, Cerrato E, Bollati M, Nombela-Franco L, Terol B, Alfonso-Rodríguez E, Camacho Freire SJ, Villablanca PA, Amat Santos IJ, de la Torre Hernández JM, Pascual I, Liebetrau C, Camacho B, Pavani M, Albistur J, Latini RA, Varbella F, Jiménez-Díaz VA, Piraino D, Mancone M, Alfonso F, Linares JA, Rodríguez-Olivares R, Jiménez Mazuecos JM, Palazuelos Molinero J, Sánchez-Grande Flecha A, Gomez-Hospital JA, Ielasi A, Lozano Í, Omedè P, Bagur R, Ugo F, Medda M, Louka BF, Kala P, Escaned J, Bautista D, Feltes G, Salinas P, Alkhouli M, Macaya C, Fernández-Ortiz A; CAAR investigators. Núñez-Gil IJ, et al. Among authors: linares ja. Int J Cardiol. 2020 Jan 15;299:49-55. doi: 10.1016/j.ijcard.2019.05.067. Epub 2019 Jul 19. Int J Cardiol. 2020. PMID: 31378382 Free article. Clinical Trial.
Hyaluronan driven by epithelial aPKC deficiency remodels the microenvironment and creates a vulnerability in mesenchymal colorectal cancer.
Martinez-Ordoñez A, Duran A, Ruiz-Martinez M, Cid-Diaz T, Zhang X, Han Q, Kinoshita H, Muta Y, Linares JF, Kasashima H, Nakanishi Y, Omar M, Nishimura S, Avila L, Yashiro M, Maeda K, Pannellini T, Pigazzi A, Inghirami G, Marchionni L, Sigal D, Diaz-Meco MT, Moscat J. Martinez-Ordoñez A, et al. Among authors: linares jf. Cancer Cell. 2023 Feb 13;41(2):252-271.e9. doi: 10.1016/j.ccell.2022.11.016. Epub 2022 Dec 15. Cancer Cell. 2023. PMID: 36525970 Free PMC article.
538 results