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2020 4
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Page 1
Longitudinal analyses reveal immunological misfiring in severe COVID-19.
Lucas C, Wong P, Klein J, Castro TBR, Silva J, Sundaram M, Ellingson MK, Mao T, Oh JE, Israelow B, Takahashi T, Tokuyama M, Lu P, Venkataraman A, Park A, Mohanty S, Wang H, Wyllie AL, Vogels CBF, Earnest R, Lapidus S, Ott IM, Moore AJ, Muenker MC, Fournier JB, Campbell M, Odio CD, Casanovas-Massana A; Yale IMPACT Team; Herbst R, Shaw AC, Medzhitov R, Schulz WL, Grubaugh ND, Dela Cruz C, Farhadian S, Ko AI, Omer SB, Iwasaki A. Lucas C, et al. Nature. 2020 Aug;584(7821):463-469. doi: 10.1038/s41586-020-2588-y. Epub 2020 Jul 27. Nature. 2020. PMID: 32717743 Free PMC article.
Diverse functional autoantibodies in patients with COVID-19.
Wang EY, Mao T, Klein J, Dai Y, Huck JD, Jaycox JR, Liu F, Zhou T, Israelow B, Wong P, Coppi A, Lucas C, Silva J, Oh JE, Song E, Perotti ES, Zheng NS, Fischer S, Campbell M, Fournier JB, Wyllie AL, Vogels CBF, Ott IM, Kalinich CC, Petrone ME, Watkins AE; Yale IMPACT Team; Dela Cruz C, Farhadian SF, Schulz WL, Ma S, Grubaugh ND, Ko AI, Iwasaki A, Ring AM. Wang EY, et al. Nature. 2021 Jul;595(7866):283-288. doi: 10.1038/s41586-021-03631-y. Epub 2021 May 19. Nature. 2021. PMID: 34010947
Multiscale PHATE identifies multimodal signatures of COVID-19.
Kuchroo M, Huang J, Wong P, Grenier JC, Shung D, Tong A, Lucas C, Klein J, Burkhardt DB, Gigante S, Godavarthi A, Rieck B, Israelow B, Simonov M, Mao T, Oh JE, Silva J, Takahashi T, Odio CD, Casanovas-Massana A, Fournier J; Yale IMPACT Team; Farhadian S, Dela Cruz CS, Ko AI, Hirn MJ, Wilson FP, Hussin JG, Wolf G, Iwasaki A, Krishnaswamy S. Kuchroo M, et al. Nat Biotechnol. 2022 May;40(5):681-691. doi: 10.1038/s41587-021-01186-x. Epub 2022 Feb 28. Nat Biotechnol. 2022. PMID: 35228707 Free PMC article.
Diverse Functional Autoantibodies in Patients with COVID-19.
Wang EY, Mao T, Klein J, Dai Y, Huck JD, Liu F, Zheng NS, Zhou T, Israelow B, Wong P, Lucas C, Silva J, Oh JE, Song E, Perotti ES, Fischer S, Campbell M, Fournier JB, Wyllie AL, Vogels CBF, Ott IM, Kalinich CC, Petrone ME, Watkins AE; Yale IMPACT Team; Cruz CD, Farhadian SF, Schulz WL, Grubaugh ND, Ko AI, Iwasaki A, Ring AM. Wang EY, et al. medRxiv [Preprint]. 2021 Feb 1:2020.12.10.20247205. doi: 10.1101/2020.12.10.20247205. medRxiv. 2021. Update in: Nature. 2021 Jul;595(7866):283-288. doi: 10.1038/s41586-021-03631-y. PMID: 33330894 Free PMC article. Updated. Preprint.
Lack of association between pandemic chilblains and SARS-CoV-2 infection.
Gehlhausen JR, Little AJ, Ko CJ, Emmenegger M, Lucas C, Wong P, Klein J, Lu P, Mao T, Jaycox J, Wang E; Yale IMPACT Team; Ugwu N, Muenker C, Mekael D, Klein RQ, Patrignelli R, Antaya R, McNiff J, Damsky W, Kamath K, Shon J, Ring AM, Yildirim I, Omer S, Ko AI, Aguzzi A, Iwasaki A. Gehlhausen JR, et al. Proc Natl Acad Sci U S A. 2022 Mar 1;119(9):e2122090119. doi: 10.1073/pnas.2122090119. Proc Natl Acad Sci U S A. 2022. PMID: 35217624 Free PMC article.
Evidence for SARS-CoV-2 Spike Protein in the Urine of COVID-19 Patients.
George S, Pal AC, Gagnon J, Timalsina S, Singh P, Vydyam P, Munshi M, Chiu JE, Renard I, Harden CA, Ott IM, Watkins AE, Vogels CBF, Lu P, Tokuyama M, Venkataraman A, Casanovas-Massana A, Wyllie AL, Rao V, Campbell M, Farhadian SF, Grubaugh ND, Dela Cruz CS, Ko AI, Berna Perez AZ, Akaho EH, Moledina DG, Testani J, John AR, Ledizet M, Mamoun CB; and the Yale IMPACT Team. George S, et al. Kidney360. 2021 Apr 14;2(6):924-936. doi: 10.34067/KID.0002172021. eCollection 2021 Jun 24. Kidney360. 2021. PMID: 35373072 Free PMC article.
High-resolution epitope mapping and characterization of SARS-CoV-2 antibodies in large cohorts of subjects with COVID-19.
Haynes WA, Kamath K, Bozekowski J, Baum-Jones E, Campbell M, Casanovas-Massana A, Daugherty PS, Dela Cruz CS, Dhal A, Farhadian SF, Fitzgibbons L, Fournier J, Jhatro M, Jordan G, Klein J, Lucas C, Kessler D, Luchsinger LL, Martinez B, Catherine Muenker M, Pischel L, Reifert J, Sawyer JR, Waitz R, Wunder EA Jr, Zhang M; Yale IMPACT Team; Iwasaki A, Ko A, Shon JC. Haynes WA, et al. Commun Biol. 2021 Nov 22;4(1):1317. doi: 10.1038/s42003-021-02835-2. Commun Biol. 2021. PMID: 34811480 Free PMC article.
Cutting Edge: Severe SARS-CoV-2 Infection in Humans Is Defined by a Shift in the Serum Lipidome, Resulting in Dysregulation of Eicosanoid Immune Mediators.
Schwarz B, Sharma L, Roberts L, Peng X, Bermejo S, Leighton I, Casanovas-Massana A, Minasyan M, Farhadian S, Ko AI; Yale IMPACT Team; Dela Cruz CS, Bosio CM. Schwarz B, et al. J Immunol. 2021 Jan 15;206(2):329-334. doi: 10.4049/jimmunol.2001025. Epub 2020 Dec 4. J Immunol. 2021. PMID: 33277388 Free PMC article. Clinical Trial.
Saliva viral load is a dynamic unifying correlate of COVID-19 severity and mortality.
Silva J, Lucas C, Sundaram M, Israelow B, Wong P, Klein J, Tokuyama M, Lu P, Venkataraman A, Liu F, Mao T, Oh JE, Park A, Casanovas-Massana A, Vogels CBF, Muenker MC, Zell J, Fournier JB, Campbell M, Chiorazzi M, Fuentes ER, Petrone ME, Kalinich CC, Ott IM, Watkins A, Moore AJ, Nakahata M; Yale IMPACT Team; Farhadian S, Cruz CD, Ko AI, Schulz WL, Ring A, Ma S, Omer S, Wyllie AL, Iwasaki A. Silva J, et al. medRxiv [Preprint]. 2021 Jan 10:2021.01.04.21249236. doi: 10.1101/2021.01.04.21249236. medRxiv. 2021. PMID: 33442706 Free PMC article. Preprint.
SARS-CoV-2 infection in pregnancy is associated with robust inflammatory response at the maternal-fetal interface.
Lu-Culligan A, Chavan AR, Vijayakumar P, Irshaid L, Courchaine EM, Milano KM, Tang Z, Pope SD, Song E, Vogels CBF, Lu-Culligan WJ, Campbell KH, Casanovas-Massana A, Bermejo S, Toothaker JM, Lee HJ, Liu F, Schulz W, Fournier J, Muenker MC, Moore AJ; Yale IMPACT Team; Konnikova L, Neugebauer KM, Ring A, Grubaugh ND, Ko AI, Morotti R, Guller S, Kliman HJ, Iwasaki A, Farhadian SF. Lu-Culligan A, et al. medRxiv [Preprint]. 2021 Jan 26:2021.01.25.21250452. doi: 10.1101/2021.01.25.21250452. medRxiv. 2021. Update in: Med. 2021 May 14;2(5):591-610.e10. doi: 10.1016/j.medj.2021.04.016. PMID: 33532791 Free PMC article. Updated. Preprint.
13 results