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2018 2
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26 results

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Page 1
Discovery of drug-omics associations in type 2 diabetes with generative deep-learning models.
Allesøe RL, Lundgaard AT, Hernández Medina R, Aguayo-Orozco A, Johansen J, Nissen JN, Brorsson C, Mazzoni G, Niu L, Biel JH, Leal Rodríguez C, Brasas V, Webel H, Benros ME, Pedersen AG, Chmura PJ, Jacobsen UP, Mari A, Koivula R, Mahajan A, Vinuela A, Tajes JF, Sharma S, Haid M, Hong MG, Musholt PB, De Masi F, Vogt J, Pedersen HK, Gudmundsdottir V, Jones A, Kennedy G, Bell J, Thomas EL, Frost G, Thomsen H, Hansen E, Hansen TH, Vestergaard H, Muilwijk M, Blom MT, 't Hart LM, Pattou F, Raverdy V, Brage S, Kokkola T, Heggie A, McEvoy D, Mourby M, Kaye J, Hattersley A, McDonald T, Ridderstråle M, Walker M, Forgie I, Giordano GN, Pavo I, Ruetten H, Pedersen O, Hansen T, Dermitzakis E, Franks PW, Schwenk JM, Adamski J, McCarthy MI, Pearson E, Banasik K, Rasmussen S, Brunak S; IMI DIRECT Consortium. Allesøe RL, et al. Nat Biotechnol. 2023 Mar;41(3):399-408. doi: 10.1038/s41587-022-01520-x. Epub 2023 Jan 2. Nat Biotechnol. 2023. PMID: 36593394 Free PMC article.
Pharmacogenomics of GLP-1 receptor agonists: a genome-wide analysis of observational data and large randomised controlled trials.
Dawed AY, Mari A, Brown A, McDonald TJ, Li L, Wang S, Hong MG, Sharma S, Robertson NR, Mahajan A, Wang X, Walker M, Gough S, Hart LM', Zhou K, Forgie I, Ruetten H, Pavo I, Bhatnagar P, Jones AG, Pearson ER; DIRECT consortium. Dawed AY, et al. Lancet Diabetes Endocrinol. 2023 Jan;11(1):33-41. doi: 10.1016/S2213-8587(22)00340-0. Lancet Diabetes Endocrinol. 2023. PMID: 36528349 Free article.
Taste alterations and cancer treatment.
van Oort S, Kramer E, de Groot JW, Visser O. van Oort S, et al. Curr Opin Support Palliat Care. 2018 Jun;12(2):162-167. doi: 10.1097/SPC.0000000000000346. Curr Opin Support Palliat Care. 2018. PMID: 29570496 Review.
Genetic analysis of blood molecular phenotypes reveals common properties in the regulatory networks affecting complex traits.
Brown AA, Fernandez-Tajes JJ, Hong MG, Brorsson CA, Koivula RW, Davtian D, Dupuis T, Sartori A, Michalettou TD, Forgie IM, Adam J, Allin KH, Caiazzo R, Cederberg H, De Masi F, Elders PJM, Giordano GN, Haid M, Hansen T, Hansen TH, Hattersley AT, Heggie AJ, Howald C, Jones AG, Kokkola T, Laakso M, Mahajan A, Mari A, McDonald TJ, McEvoy D, Mourby M, Musholt PB, Nilsson B, Pattou F, Penet D, Raverdy V, Ridderstråle M, Romano L, Rutters F, Sharma S, Teare H, 't Hart L, Tsirigos KD, Vangipurapu J, Vestergaard H, Brunak S, Franks PW, Frost G, Grallert H, Jablonka B, McCarthy MI, Pavo I, Pedersen O, Ruetten H, Walker M; DIRECT Consortium; Adamski J, Schwenk JM, Pearson ER, Dermitzakis ET, Viñuela A. Brown AA, et al. Nat Commun. 2023 Aug 21;14(1):5062. doi: 10.1038/s41467-023-40569-3. Nat Commun. 2023. PMID: 37604891 Free PMC article.
Alcohol consumption in relation to cardiovascular diseases and mortality: a systematic review of Mendelian randomization studies.
van de Luitgaarden IAT, van Oort S, Bouman EJ, Schoonmade LJ, Schrieks IC, Grobbee DE, van der Schouw YT, Larsson SC, Burgess S, van Ballegooijen AJ, Onland-Moret NC, Beulens JWJ. van de Luitgaarden IAT, et al. Among authors: van oort s. Eur J Epidemiol. 2022 Jul;37(7):655-669. doi: 10.1007/s10654-021-00799-5. Epub 2021 Aug 22. Eur J Epidemiol. 2022. PMID: 34420153 Free PMC article. Review.
Inflammation and heart failure: a two-sample Mendelian randomization study.
Remmelzwaal S, van Oort S, Handoko ML, van Empel V, Heymans SRB, Beulens JWJ. Remmelzwaal S, et al. Among authors: van oort s. J Cardiovasc Med (Hagerstown). 2022 Nov 1;23(11):728-735. doi: 10.2459/JCM.0000000000001373. Epub 2022 Sep 7. J Cardiovasc Med (Hagerstown). 2022. PMID: 36166332
26 results