The Pietà study: epidemiological investigation on successful brain aging in Caeté (MG), Brazil. Methods and baseline cohort characteristics

Arq Neuropsiquiatr. 2011 Aug;69(4):579-84. doi: 10.1590/s0004-282x2011000500002.

Abstract

Objectives: To present the methods and baseline characteristics of the Pietà study, a population-based survey investigating successful brain aging in the oldest-old.

Method: The study was conducted in Caeté (MG), Brazil. In 2007, 1,251 individuals aged 75+ years were living in the city and were invited to participate. Participants responded to a general health questionnaire and were submitted to clinical, neurological, cognitive, psychiatric and functional evaluations. A subgroup was submitted to neuropsychological testing, blood tests and magnetic resonance of the skull. Individuals were classified as having cognitive impairment-no dementia, dementia, parkinsonism, psychiatric disorders or successful brain aging.

Results: We evaluated 639 individuals (51.1% of the target population; 64% women), aged 81.4±5.2 years and with 2.7±2.6 years of schooling. Almost 30% of the elderly were illiterates and 82.1% belonged to middle/middle-low socioeconomic levels. Almost 50% were widows, but only 14.3% were living alone.

Conclusion: The Pietà cohort is representative of the oldest-old Brazilian population. We believe the results of the study may contribute to increase our knowledge about healthy and pathological brain aging in the oldest-old.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Aged, 80 and over
  • Aging / physiology*
  • Brazil / epidemiology
  • Cognition Disorders / epidemiology*
  • Cognition Disorders / physiopathology
  • Cohort Studies
  • Dementia / epidemiology
  • Dementia / physiopathology
  • Female
  • Geriatric Assessment / methods*
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Mental Disorders / epidemiology
  • Mental Disorders / physiopathology
  • Neuropsychological Tests
  • Parkinson Disease / epidemiology
  • Parkinson Disease / physiopathology
  • Socioeconomic Factors