Executive summary of the consensus document on post-exposure prophylaxis against HIV, HBV and HCV in adults and children

Enferm Infecc Microbiol Clin. 2016 Feb;34(2):122-31. doi: 10.1016/j.eimc.2015.08.004. Epub 2015 Oct 23.

Abstract

Post-exposure prophylaxis (PEP) can be a secondary measure to prevent infection by human immunodeficiency virus (HIV) when primary prevention has failed. PEP is advised for people with sporadic and exceptional risk exposure to HIV. This consensus document about occupational and non-occupational PEP recommendations aims to be a technical document for healthcare professionals. Its main objective is to facilitate the appropriate use of PEP. To this end, some recommendations have been established to assess the risk of transmission in different types of exposure, situations where PEP should be recommended, special circumstances to take into account, antiretroviral (ARV) guidelines including start and end of the treatment, early monitoring of tolerance and adherence to the treatment, subsequent monitoring of people exposed, independently of having received PEP or not, and need of psychological support. This document is intended for all professionals who work in clinical practice in the field of HIV infection.

Keywords: HIV, HBV, HVC; Non-occupational postexposure prophylaxis; Occupational postexposure prophylaxis; Profilaxis postexposición no ocupacional; Profilaxis postexposición ocupacional; VIH, VHB, VHC.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Anti-HIV Agents / therapeutic use
  • Antiviral Agents / therapeutic use
  • Child
  • Consensus
  • HIV Infections / drug therapy*
  • Hepatitis B / drug therapy*
  • Hepatitis C / drug therapy*
  • Humans
  • Occupational Exposure / prevention & control
  • Post-Exposure Prophylaxis*
  • Practice Guidelines as Topic

Substances

  • Anti-HIV Agents
  • Antiviral Agents